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Dermoscopic Findings of Alopecia in Patients with Hypothyroidism
BACKGROUND: Thyroid hormones are essential for the growth and maintenance of hair follicles. Numerous studies have evaluated the relationship between thyroid disorders and hair loss. However, no study has assessed the dermoscopic results in patients with hypothyroidism and hair loss. OBJECTIVES: Thi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Brieflands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871962/ https://www.ncbi.nlm.nih.gov/pubmed/36714186 http://dx.doi.org/10.5812/ijem-128938 |
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author | Gharaei Nejad, Kaveh Motamed, Behrang Hassanzadeh Rad, Afagh Rafiee, Elahe Dalili, Setila Molaei, Atrie |
author_facet | Gharaei Nejad, Kaveh Motamed, Behrang Hassanzadeh Rad, Afagh Rafiee, Elahe Dalili, Setila Molaei, Atrie |
author_sort | Gharaei Nejad, Kaveh |
collection | PubMed |
description | BACKGROUND: Thyroid hormones are essential for the growth and maintenance of hair follicles. Numerous studies have evaluated the relationship between thyroid disorders and hair loss. However, no study has assessed the dermoscopic results in patients with hypothyroidism and hair loss. OBJECTIVES: This study aimed to investigate dermoscopic findings of alopecia in patients with hypothyroidism. METHODS: This analytic cross-sectional study was performed on patients with hair loss referred to dermatology clinics of Guilan University of Medical Sciences, Iran. Hypothyroid patients and an equal number of euthyroid individuals were compared. After recording the demographic and clinical characteristics, all patients were subjected to hair dermoscopy. RESULTS: A total of 164 patients with and without hypothyroidism with hair loss were studied. The frequency of hair shaft abnormalities (P < 0.001) and vellus hair (P < 0.001) significantly differed between the two groups. Dermoscopic findings related to scale abnormalities (P = 0.002) and their perifollicular type (P < 0.001) significantly differed between the groups. Vascular changes (P < 0.001), perifollicular concentric type (P = 0.012), and interfollicular red loops type (P = 0.005) were significantly higher in patients with hypothyroidism. Also, based on the multiple logistic regression model, the chance of abnormalities of the hair shaft, scales, and vascular changes increased by 3.24, 2.73, and 3.53, respectively, in hypothyroidism compared to euthyroidism. CONCLUSIONS: Regarding the promising results of this study, we could detect possible dermoscopic signs of inflammation in hypothyroid patients with hair loss. Further investigations are needed because there is a shortage of evidence on this novel diagnostic method. |
format | Online Article Text |
id | pubmed-9871962 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Brieflands |
record_format | MEDLINE/PubMed |
spelling | pubmed-98719622023-01-28 Dermoscopic Findings of Alopecia in Patients with Hypothyroidism Gharaei Nejad, Kaveh Motamed, Behrang Hassanzadeh Rad, Afagh Rafiee, Elahe Dalili, Setila Molaei, Atrie Int J Endocrinol Metab Research Article BACKGROUND: Thyroid hormones are essential for the growth and maintenance of hair follicles. Numerous studies have evaluated the relationship between thyroid disorders and hair loss. However, no study has assessed the dermoscopic results in patients with hypothyroidism and hair loss. OBJECTIVES: This study aimed to investigate dermoscopic findings of alopecia in patients with hypothyroidism. METHODS: This analytic cross-sectional study was performed on patients with hair loss referred to dermatology clinics of Guilan University of Medical Sciences, Iran. Hypothyroid patients and an equal number of euthyroid individuals were compared. After recording the demographic and clinical characteristics, all patients were subjected to hair dermoscopy. RESULTS: A total of 164 patients with and without hypothyroidism with hair loss were studied. The frequency of hair shaft abnormalities (P < 0.001) and vellus hair (P < 0.001) significantly differed between the two groups. Dermoscopic findings related to scale abnormalities (P = 0.002) and their perifollicular type (P < 0.001) significantly differed between the groups. Vascular changes (P < 0.001), perifollicular concentric type (P = 0.012), and interfollicular red loops type (P = 0.005) were significantly higher in patients with hypothyroidism. Also, based on the multiple logistic regression model, the chance of abnormalities of the hair shaft, scales, and vascular changes increased by 3.24, 2.73, and 3.53, respectively, in hypothyroidism compared to euthyroidism. CONCLUSIONS: Regarding the promising results of this study, we could detect possible dermoscopic signs of inflammation in hypothyroid patients with hair loss. Further investigations are needed because there is a shortage of evidence on this novel diagnostic method. Brieflands 2022-10-11 /pmc/articles/PMC9871962/ /pubmed/36714186 http://dx.doi.org/10.5812/ijem-128938 Text en Copyright © 2022, International Journal of Endocrinology and Metabolism https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Research Article Gharaei Nejad, Kaveh Motamed, Behrang Hassanzadeh Rad, Afagh Rafiee, Elahe Dalili, Setila Molaei, Atrie Dermoscopic Findings of Alopecia in Patients with Hypothyroidism |
title | Dermoscopic Findings of Alopecia in Patients with Hypothyroidism |
title_full | Dermoscopic Findings of Alopecia in Patients with Hypothyroidism |
title_fullStr | Dermoscopic Findings of Alopecia in Patients with Hypothyroidism |
title_full_unstemmed | Dermoscopic Findings of Alopecia in Patients with Hypothyroidism |
title_short | Dermoscopic Findings of Alopecia in Patients with Hypothyroidism |
title_sort | dermoscopic findings of alopecia in patients with hypothyroidism |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871962/ https://www.ncbi.nlm.nih.gov/pubmed/36714186 http://dx.doi.org/10.5812/ijem-128938 |
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