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Decitabine improves MMS-induced retinal photoreceptor cell damage by targeting DNMT3A and DNMT3B

INTRODUCTION: Retinitis pigmentosa (RP) is a group of neurodegenerative retinopathies causing blindness due to progressive and irreversible photoreceptor cell death. The alkylating agent methyl methanesulfonate (MMS) can induce selective photoreceptor cell death, which is used to establish RP animal...

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Detalles Bibliográficos
Autores principales:	Ji, Yanli, Zhao, Meng, Qiao, Xiaomeng, Peng, Guang-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872157/ https://www.ncbi.nlm.nih.gov/pubmed/36704326 http://dx.doi.org/10.3389/fnmol.2022.1057365

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