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6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice

OBJECTIVE: Dietary fibres are essential for maintaining microbial diversity and the gut microbiota can modulate host physiology by metabolising the fibres. Here, we investigated whether the soluble dietary fibre oligofructose improves host metabolism by modulating bacterial transformation of seconda...

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Detalles Bibliográficos
Autores principales:	Makki, Kassem, Brolin, Harald, Petersen, Natalia, Henricsson, Marcus, Christensen, Dan Ploug, Khan, Muhammad Tanweer, Wahlström, Annika, Bergh, Per-Olof, Tremaroli, Valentina, Schoonjans, Kristina, Marschall, Hanns-Ulrich, Bäckhed, Fredrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Gut Microbiota
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872241/ https://www.ncbi.nlm.nih.gov/pubmed/35697422 http://dx.doi.org/10.1136/gutjnl-2021-326541

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