Cargando…

Accurate liquid biopsy for the diagnosis of non-alcoholic steatohepatitis and liver fibrosis

OBJECTIVE: Clinical diagnosis and approval of new medications for non-alcoholic steatohepatitis (NASH) require invasive liver biopsies. The aim of our study was to identify non-invasive biomarkers of NASH and/or liver fibrosis. DESIGN: This multicentre study includes 250 patients (discovery cohort,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Angelini, Giulia, Panunzi, Simona, Castagneto-Gissey, Lidia, Pellicanò, Francesca, De Gaetano, Andrea, Pompili, Maurizio, Riccardi, Laura, Garcovich, Matteo, Raffaelli, Marco, Ciccoritti, Luigi, Verrastro, Ornella, Russo, Maria Francesca, Vecchio, Fabio Maria, Casella, Giovanni, Casella-Mariolo, James, Papa, Luigi, Marini, Pier Luigi, Rubino, Francesco, le Roux, Carel W, Bornstein, Stefan, Mingrone, Geltrude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872242/ https://www.ncbi.nlm.nih.gov/pubmed/35820779 http://dx.doi.org/10.1136/gutjnl-2022-327498

Ejemplares similares

Obesity Surgery and Cancer: What Are the Unanswered Questions?
por: Castagneto-Gissey, Lidia, et al.
Publicado: (2020)

Simulation of gastric bypass effects on glucose metabolism and non-alcoholic fatty liver disease with the Sleeveballoon device
por: Casella-Mariolo, James, et al.
Publicado: (2019)

Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis
por: Angelini, Giulia, et al.
Publicado: (2022)

The Role of Antibiotic Prophylaxis in Anastomotic Leak Prevention during Elective Colorectal Surgery: Systematic Review and Meta-Analysis of Randomized Controlled Trials
por: Castagneto-Gissey, Lidia, et al.
Publicado: (2023)

The early reduction of left ventricular mass after sleeve gastrectomy depends on the fall of branched-chain amino acid circulating levels
por: Castagneto-Gissey, Lidia, et al.
Publicado: (2022)

Publisher Correction: New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery
por: Angelini, Giulia, et al.
Publicado: (2020)

New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery
por: Angelini, Giulia, et al.
Publicado: (2019)

Intracholecystic versus Intravenous Indocyanine Green (ICG) Injection for Biliary Anatomy Evaluation by Fluorescent Cholangiography during Laparoscopic Cholecystectomy: A Case–Control Study
por: Castagneto-Gissey, Lidia, et al.
Publicado: (2022)

Efficacy of Sleeve Gastrectomy with Concomitant Hiatal Hernia Repair versus Sleeve–Fundoplication on Gastroesophageal Reflux Disease Resolution: Systematic Review and Meta-Analysis
por: Castagneto-Gissey, Lidia, et al.
Publicado: (2023)

Incidence of lymphomas in inflammatory bowel disease: report of an emblematic case, systematic review, and meta-analysis
por: Russo, Maria Francesca, et al.
Publicado: (2023)

Insulin Dynamics in Young Women with Polycystic Ovary Syndrome and Normal Glucose Tolerance across Categories of Body Mass Index
por: Manco, Melania, et al.
Publicado: (2014)

Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis
por: Koh, Eun Hee, et al.
Publicado: (2021)

Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors
por: Wieser, Verena, et al.
Publicado: (2017)

Reliability and validity of the Chronic Liver Disease Questionnaire (CLDQ) in adults with non-alcoholic steatohepatitis (NASH)
por: Chawla, Kashmira S, et al.
Publicado: (2016)

Novel Modality of Endoluminal Anastomotic Integrity Assessment with Fluoroangiography After Left-sided Colorectal Resections
por: Castagneto-Gissey, Lidia, et al.
Publicado: (2023)

Relationship between Streptococcus mutans expressing Cnm in the oral cavity and non-alcoholic steatohepatitis: a pilot study
por: Tonomura, Shuichi, et al.
Publicado: (2019)

Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance
por: Sun, Nannan, et al.
Publicado: (2021)

Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression
por: Loyer, Xavier, et al.
Publicado: (2016)

Thyroid Hormones and Thyromimetics: A New Approach to Nonalcoholic Steatohepatitis?
por: Sinha, Rohit A., et al.
Publicado: (2020)

Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test
por: Panunzi, Simona, et al.
Publicado: (2010)

Medium-Term Nutritional and Metabolic Outcome of Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy (SADI-S)
por: Marincola, Giuseppe, et al.
Publicado: (2023)

New case of syncytial giant-cell variant of hepatocellular carcinoma in a pediatric patient with HNF1B deficiency: does it fit with the syndrome?
por: Pinon, Michele, et al.
Publicado: (2022)

Editorial: Women in surgical oncology vol II: 2022
por: Castagneto-Gissey, Lidia
Publicado: (2023)

A new sensitive and accurate model to predict moderate to severe obstructive sleep apnea in patients with obesity
por: Ahlin, Sofie, et al.
Publicado: (2019)

Nonalcoholic steatohepatitis diagnosis and treatment from the perspective of patients and primary care physicians: a cross-sectional survey
por: Nadolsky, Karl, et al.
Publicado: (2023)

Protocol for a randomised clinical study comparing the effect of Roux-en-Y gastric bypass and sleeve gastrectomy on reactive hypoglycaemia in morbidly obese subjects
por: Mingrone, Geltrude, et al.
Publicado: (2012)

Effects of Bilio-Pancreatic Diversion on Diabetic Complications: A 10-year follow-up
por: Iaconelli, Amerigo, et al.
Publicado: (2011)

A comparative study on roles of natural killer T cells in two diet-induced non-alcoholic steatohepatitis-related fibrosis in mice
por: Zheng, Shumei, et al.
Publicado: (2022)

Robotic vs laparoscopic approach for single anastomosis duodenal-ileal bypass with sleeve gastrectomy: a propensity score matching analysis
por: Pennestrì, Francesco, et al.
Publicado: (2022)

Influence of sex in alcohol‐related liver disease: Pre‐clinical and clinical settings
por: Bizzaro, Debora, et al.
Publicado: (2023)

Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial
por: Armstrong, Matthew J, et al.
Publicado: (2013)

Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial
por: Pinyol, Roser, et al.
Publicado: (2019)

Apoptosis and diagnosis of nonalcoholic steatohepatitis
por: Kim, Chang Wook, et al.
Publicado: (2011)

Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription
por: Salerno, Debora, et al.
Publicado: (2020)

Spider surgical system versus multiport laparoscopic surgery: performance comparison on a surgical simulator
por: Giannotti, Domenico, et al.
Publicado: (2015)

The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa
por: Lemoine, Maud, et al.
Publicado: (2016)

Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B
por: Svicher, Valentina, et al.
Publicado: (2021)

Assessing the obese diabetic patient for bariatric surgery: which candidate do I choose?
por: Raffaelli, Marco, et al.
Publicado: (2015)

Correlation between a New Point-Shear Wave Elastography Device (X+pSWE) with Liver Histology and 2D-SWE (SSI) for Liver Stiffness Quantification in Chronic Liver Disease
por: Garcovich, Matteo, et al.
Publicado: (2023)

Suppressor CD4(+) T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis
por: Khamri, Wafa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5nakqnpq57o9vmlb71pfaqjipv