Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma

OBJECTIVE: The lysyl oxidase-like protein 2 (LOXL2) contributes to tumour progression and metastasis in different tumour entities, but its role in pancreatic ductal adenocarcinoma (PDAC) has not been evaluated in immunocompetent in vivo PDAC models. DESIGN: Towards this end, we used PDAC patient dat...

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Detalles Bibliográficos
Autores principales: Alonso-Nocelo, Marta, Ruiz-Cañas, Laura, Sancho, Patricia, Görgülü, Kıvanç, Alcalá, Sonia, Pedrero, Coral, Vallespinos, Mireia, López-Gil, Juan Carlos, Ochando, Marina, García-García, Elena, David Trabulo, Sara Maria, Martinelli, Paola, Sánchez-Tomero, Patricia, Sánchez-Palomo, Carmen, Gonzalez-Santamaría, Patricia, Yuste, Lourdes, Wörmann, Sonja Maria, Kabacaoğlu, Derya, Earl, Julie, Martin, Alberto, Salvador, Fernando, Valle, Sandra, Martin-Hijano, Laura, Carrato, Alfredo, Erkan, Mert, García-Bermejo, Laura, Hermann, Patrick C, Algül, Hana, Moreno-Bueno, Gema, Heeschen, Christopher, Portillo, Francisco, Cano, Amparo, Sainz, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872246/
https://www.ncbi.nlm.nih.gov/pubmed/35428659
http://dx.doi.org/10.1136/gutjnl-2021-325564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872246/
https://www.ncbi.nlm.nih.gov/pubmed/35428659
http://dx.doi.org/10.1136/gutjnl-2021-325564

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