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Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture

BACKGROUND: Because of their poor physical state, elderly hip fracture patients commonly require prolonged hospitalization, resulting in a drop in bed circulation rate and an increased financial burden. There are currently few predictive models for delayed hospital discharge for hip fractures. This...

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Autores principales: Cao, Hong, Yu, Jian, Chang, YaRu, Li, Yue, Zhou, Bingqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872294/
https://www.ncbi.nlm.nih.gov/pubmed/36694160
http://dx.doi.org/10.1186/s12891-023-06166-7
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author Cao, Hong
Yu, Jian
Chang, YaRu
Li, Yue
Zhou, Bingqian
author_facet Cao, Hong
Yu, Jian
Chang, YaRu
Li, Yue
Zhou, Bingqian
author_sort Cao, Hong
collection PubMed
description BACKGROUND: Because of their poor physical state, elderly hip fracture patients commonly require prolonged hospitalization, resulting in a drop in bed circulation rate and an increased financial burden. There are currently few predictive models for delayed hospital discharge for hip fractures. This research aimed to develop the optimal model for delayed hospital discharge for hip fractures in order to support clinical decision-making. METHODS: This case-control research consisted of 1259 patients who were continuously hospitalized in the orthopedic unit of an acute hospital in Tianjin due to a fragility hip fracture between January and December 2021. Delayed discharge was defined as a hospital stay of more than 11 days. The prediction model was constructed through the use of a Cox proportional hazards regression model. Furthermore, the constructed prediction model was transformed into a nomogram. The model’s performance was assessed using the area under the receiver operating characteristic curve (AUC), calibration curves and decision curve analysis (DCA). the STROBE checklist was used as the reporting guideline. RESULTS: The risk prediction model developed contained the Charlson Comorbidity Index (CCI), preoperative waiting time, anemia, hypoalbuminemia, and lower limbs arteriosclerosis. The AUC for the risk of delayed discharge was in the training set was 0.820 (95% CI,0.79 ~ 0.85) and 0.817 in the testing sets. The calibration revealed that the forecasted cumulative risk and observed probability of delayed discharge were quite similar. Using the risk prediction model, a higher net benefit was observed than when considered all patients were at high risk, demonstrating good clinical usefulness. CONCLUSION: Our prediction models could support policymakers in developing strategies for the optimal management of hip fracture patients, with a particular emphasis on individuals at high risk of prolonged LOS.
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spelling pubmed-98722942023-01-25 Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture Cao, Hong Yu, Jian Chang, YaRu Li, Yue Zhou, Bingqian BMC Musculoskelet Disord Research BACKGROUND: Because of their poor physical state, elderly hip fracture patients commonly require prolonged hospitalization, resulting in a drop in bed circulation rate and an increased financial burden. There are currently few predictive models for delayed hospital discharge for hip fractures. This research aimed to develop the optimal model for delayed hospital discharge for hip fractures in order to support clinical decision-making. METHODS: This case-control research consisted of 1259 patients who were continuously hospitalized in the orthopedic unit of an acute hospital in Tianjin due to a fragility hip fracture between January and December 2021. Delayed discharge was defined as a hospital stay of more than 11 days. The prediction model was constructed through the use of a Cox proportional hazards regression model. Furthermore, the constructed prediction model was transformed into a nomogram. The model’s performance was assessed using the area under the receiver operating characteristic curve (AUC), calibration curves and decision curve analysis (DCA). the STROBE checklist was used as the reporting guideline. RESULTS: The risk prediction model developed contained the Charlson Comorbidity Index (CCI), preoperative waiting time, anemia, hypoalbuminemia, and lower limbs arteriosclerosis. The AUC for the risk of delayed discharge was in the training set was 0.820 (95% CI,0.79 ~ 0.85) and 0.817 in the testing sets. The calibration revealed that the forecasted cumulative risk and observed probability of delayed discharge were quite similar. Using the risk prediction model, a higher net benefit was observed than when considered all patients were at high risk, demonstrating good clinical usefulness. CONCLUSION: Our prediction models could support policymakers in developing strategies for the optimal management of hip fracture patients, with a particular emphasis on individuals at high risk of prolonged LOS. BioMed Central 2023-01-24 /pmc/articles/PMC9872294/ /pubmed/36694160 http://dx.doi.org/10.1186/s12891-023-06166-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Cao, Hong
Yu, Jian
Chang, YaRu
Li, Yue
Zhou, Bingqian
Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
title Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
title_full Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
title_fullStr Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
title_full_unstemmed Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
title_short Construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
title_sort construction and validation of a risk prediction model for delayed discharge in elderly patients with hip fracture
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872294/
https://www.ncbi.nlm.nih.gov/pubmed/36694160
http://dx.doi.org/10.1186/s12891-023-06166-7
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