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Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer

BACKGROUND: Precision medicine with gene panel testing based on next-generation sequencing for patients with cancer is being used increasingly in clinical practice. HER2, which encodes the human epidermal growth factor receptor 2 (HER2), is a potentially important driver gene. However, therapeutic s...

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Detalles Bibliográficos
Autores principales:	Harada, Yohei, Sato, Akemi, Nakamura, Hideaki, Kai, Keita, Kitamura, Sho, Nakamura, Tomomi, Kurihara, Yuki, Ikeda, Sadakatsu, Sueoka, Eisaburo, Kimura, Shinya, Sueoka-Aragane, Naoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872313/ https://www.ncbi.nlm.nih.gov/pubmed/36690964 http://dx.doi.org/10.1186/s12885-022-10428-3

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