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Mouse α-Defensins: Structural and Functional Analysis of the 17 Cryptdin Isoforms Identified from a Single Jejunal Crypt

Mouse α-defensins, better known as cryptdins, are host protective antimicrobial peptides produced in the intestinal crypt by Paneth cells. To date, more than 20 cryptdin mRNAs have been identified from mouse small intestine, of which the first six cryptdins (Crp1 to Crp6) have been isolated and char...

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Detalles Bibliográficos
Autores principales: Wang, Qingxia, Yang, Yilin, Luo, Gan, Zhou, Yang, Tolbert, William D., Pazgier, Marzena, Liao, Chongbing, Lu, Wuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872612/
https://www.ncbi.nlm.nih.gov/pubmed/36472443
http://dx.doi.org/10.1128/iai.00361-22