Human Metastatic Cholangiocarcinoma Patient-Derived Xenografts and Tumoroids for Preclinical Drug Evaluation

PURPOSE: Cholangiocarcinoma (CCA) is usually diagnosed at advanced stages, with limited therapeutic options. Preclinical models focused on unresectable metastatic CCA are necessary to develop rational treatments. Pathogenic mutations in IDH1/2, ARID1A/B, BAP1, and BRCA1/2 have been identified in 30%...

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Detalles Bibliográficos
Autores principales: Serra-Camprubí, Queralt, Verdaguer, Helena, Oliveros, Winona, Lupión-Garcia, Núria, Llop-Guevara, Alba, Molina, Cristina, Vila-Casadesús, Maria, Turpin, Anthony, Neuzillet, Cindy, Frigola, Joan, Querol, Jessica, Yáñez-Bartolomé, Mariana, Castet, Florian, Fabregat-Franco, Carles, Escudero-Iriarte, Carmen, Escorihuela, Marta, Arenas, Enrique J., Bernadó-Morales, Cristina, Haro, Noemí, Giles, Francis J., Pozo, Óscar J., Miquel, Josep M., Nuciforo, Paolo G., Vivancos, Ana, Melé, Marta, Serra, Violeta, Arribas, Joaquín, Tabernero, Josep, Peiró, Sandra, Macarulla, Teresa, Tian, Tian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873249/
https://www.ncbi.nlm.nih.gov/pubmed/36374558
http://dx.doi.org/10.1158/1078-0432.CCR-22-2551

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