Cargando…
In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer
Inhibiting a specific target in cancer cells and reducing unwanted side effects has become a promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic cancer development and correlates with poor clinical outcomes. By phosphorylating MKK4, proteins associated with cell a...
Autores principales: | Chang, Chao-Di, Chao, Min-Wu, Lee, Hsueh-Yun, Liu, Yi-Ting, Tu, Huang-Ju, Lien, Ssu-Ting, Lin, Tony Eight, Sung, Tzu-Ying, Yen, Shih-Chung, Huang, Sing-Han, Hsu, Kai-Cheng, Pan, Shiow-Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873280/ https://www.ncbi.nlm.nih.gov/pubmed/36683274 http://dx.doi.org/10.1080/14756366.2023.2166039 |
Ejemplares similares
-
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
por: Chao, Min-Wu, et al.
Publicado: (2020) -
Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol
por: Lee, Szu, et al.
Publicado: (2023) -
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
por: Lin, Chao-Feng, et al.
Publicado: (2020) -
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
por: Hsu, Kai-Cheng, et al.
Publicado: (2020) -
Urolithin A exhibits a neuroprotective effect against Alzheimer’s disease by inhibiting DYRK1A activity
por: Tu, Huang-Ju, et al.
Publicado: (2023)