Cargando…

PD-L1 Upregulation by the mTOR Pathway in VEGFR-TKI–Resistant Metastatic Clear Cell Renal Cell Carcinoma

PURPOSE: Tyrosine kinase inhibitors (TKI) targeting vascular endothelial growth factor receptor (VEGFR) signaling pathways have been used for metastatic clear cell renal cell carcinoma (mCCRCC), but resistance to the drug develops in most patients. We aimed to explore the underlying mechanism of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Se Un, Hwang, Hee Sang, Park, Ja-Min, Yoon, Sun Young, Shin, Su-Jin, Go, Heounjeong, Lee, Jae-Lyun, Jeong, Gowun, Cho, Yong Mee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873321/
https://www.ncbi.nlm.nih.gov/pubmed/35240013
http://dx.doi.org/10.4143/crt.2021.1526