T-cell activation Rho GTPase-activating protein maintains intestinal homeostasis by regulating intestinal T helper cells differentiation through the gut microbiota

Common variants of the T-cell activation Rho GTPase-activating protein (TAGAP) are associated with the susceptibility to human inflammatory bowel diseases (IBDs); however, the underlying mechanisms are still unknown. Here, we show that TAGAP deficiency or TAGAP expression downregulation caused by TA...

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Detalles Bibliográficos
Autores principales: He, Ruirui, Chen, Jianwen, Zhao, Ziyan, Shi, Changping, Du, Yanyun, Yi, Ming, Feng, Lingyun, Peng, Qianwen, Cui, Zhihui, Gao, Ru, Wang, Heping, Huang, Yi, Liu, Zhi, Wang, Chenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873376/
https://www.ncbi.nlm.nih.gov/pubmed/36704549
http://dx.doi.org/10.3389/fmicb.2022.1030947

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