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Herringbone micromixers for particle filtration

Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are typically used for mixing fluids faster than the rate of diffusion, there has been recent interest in using the device to enhance interactions between suspended particles and chann...

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Detalles Bibliográficos
Autores principales: Binsley, Jacob L., Myers, Thomas O., Pagliara, Stefano, Ogrin, Feodor Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873379/
https://www.ncbi.nlm.nih.gov/pubmed/36704613
http://dx.doi.org/10.1063/5.0134431
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author Binsley, Jacob L.
Myers, Thomas O.
Pagliara, Stefano
Ogrin, Feodor Y.
author_facet Binsley, Jacob L.
Myers, Thomas O.
Pagliara, Stefano
Ogrin, Feodor Y.
author_sort Binsley, Jacob L.
collection PubMed
description Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are typically used for mixing fluids faster than the rate of diffusion, there has been recent interest in using the device to enhance interactions between suspended particles and channel walls. We show how the common approximations applied to herringbone micromixer theory can have a significant impact on results. We show that the inclusion of gravity can greatly alter the interaction probability between suspended particles and channel walls. We also investigate the proposed impedance matching condition and the inclusion of imperfect binding using numerical methods, and investigate transient behaviors using an experimental system. These results indicate that while traditional methods, such as simple streamline analysis, remain powerful tools, it should not be considered predictive in the general case.
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spelling pubmed-98733792023-01-25 Herringbone micromixers for particle filtration Binsley, Jacob L. Myers, Thomas O. Pagliara, Stefano Ogrin, Feodor Y. Biomicrofluidics Regular Articles Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are typically used for mixing fluids faster than the rate of diffusion, there has been recent interest in using the device to enhance interactions between suspended particles and channel walls. We show how the common approximations applied to herringbone micromixer theory can have a significant impact on results. We show that the inclusion of gravity can greatly alter the interaction probability between suspended particles and channel walls. We also investigate the proposed impedance matching condition and the inclusion of imperfect binding using numerical methods, and investigate transient behaviors using an experimental system. These results indicate that while traditional methods, such as simple streamline analysis, remain powerful tools, it should not be considered predictive in the general case. AIP Publishing LLC 2023-01-23 /pmc/articles/PMC9873379/ /pubmed/36704613 http://dx.doi.org/10.1063/5.0134431 Text en © 2023 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Regular Articles
Binsley, Jacob L.
Myers, Thomas O.
Pagliara, Stefano
Ogrin, Feodor Y.
Herringbone micromixers for particle filtration
title Herringbone micromixers for particle filtration
title_full Herringbone micromixers for particle filtration
title_fullStr Herringbone micromixers for particle filtration
title_full_unstemmed Herringbone micromixers for particle filtration
title_short Herringbone micromixers for particle filtration
title_sort herringbone micromixers for particle filtration
topic Regular Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873379/
https://www.ncbi.nlm.nih.gov/pubmed/36704613
http://dx.doi.org/10.1063/5.0134431
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