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Herringbone micromixers for particle filtration
Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are typically used for mixing fluids faster than the rate of diffusion, there has been recent interest in using the device to enhance interactions between suspended particles and chann...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873379/ https://www.ncbi.nlm.nih.gov/pubmed/36704613 http://dx.doi.org/10.1063/5.0134431 |
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author | Binsley, Jacob L. Myers, Thomas O. Pagliara, Stefano Ogrin, Feodor Y. |
author_facet | Binsley, Jacob L. Myers, Thomas O. Pagliara, Stefano Ogrin, Feodor Y. |
author_sort | Binsley, Jacob L. |
collection | PubMed |
description | Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are typically used for mixing fluids faster than the rate of diffusion, there has been recent interest in using the device to enhance interactions between suspended particles and channel walls. We show how the common approximations applied to herringbone micromixer theory can have a significant impact on results. We show that the inclusion of gravity can greatly alter the interaction probability between suspended particles and channel walls. We also investigate the proposed impedance matching condition and the inclusion of imperfect binding using numerical methods, and investigate transient behaviors using an experimental system. These results indicate that while traditional methods, such as simple streamline analysis, remain powerful tools, it should not be considered predictive in the general case. |
format | Online Article Text |
id | pubmed-9873379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-98733792023-01-25 Herringbone micromixers for particle filtration Binsley, Jacob L. Myers, Thomas O. Pagliara, Stefano Ogrin, Feodor Y. Biomicrofluidics Regular Articles Herringbone micromixers are a powerful tool for introducing advection into microfluidic systems. While these mixers are typically used for mixing fluids faster than the rate of diffusion, there has been recent interest in using the device to enhance interactions between suspended particles and channel walls. We show how the common approximations applied to herringbone micromixer theory can have a significant impact on results. We show that the inclusion of gravity can greatly alter the interaction probability between suspended particles and channel walls. We also investigate the proposed impedance matching condition and the inclusion of imperfect binding using numerical methods, and investigate transient behaviors using an experimental system. These results indicate that while traditional methods, such as simple streamline analysis, remain powerful tools, it should not be considered predictive in the general case. AIP Publishing LLC 2023-01-23 /pmc/articles/PMC9873379/ /pubmed/36704613 http://dx.doi.org/10.1063/5.0134431 Text en © 2023 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Regular Articles Binsley, Jacob L. Myers, Thomas O. Pagliara, Stefano Ogrin, Feodor Y. Herringbone micromixers for particle filtration |
title | Herringbone micromixers for particle filtration |
title_full | Herringbone micromixers for particle filtration |
title_fullStr | Herringbone micromixers for particle filtration |
title_full_unstemmed | Herringbone micromixers for particle filtration |
title_short | Herringbone micromixers for particle filtration |
title_sort | herringbone micromixers for particle filtration |
topic | Regular Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873379/ https://www.ncbi.nlm.nih.gov/pubmed/36704613 http://dx.doi.org/10.1063/5.0134431 |
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