Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting

Acute lymphoblastic leukemia is predominately a childhood disease and around two third of cases are of B-cell phenotype. Cytomegalovirus is an important cause of morbidity and mortality in allogeneic hematopoietic progenitor cell transplant; however, it is rare in patients with B-cell acute lymphobl...

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Autores principales: Abbas, Mansoor, Bin Naeem, Sameen, Jhatial, Mussadique Ali, Bokhari, Syed W, Ahsan, Bushra, Ahmad, Usman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873483/
https://www.ncbi.nlm.nih.gov/pubmed/36712765
http://dx.doi.org/10.7759/cureus.32936
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author Abbas, Mansoor
Bin Naeem, Sameen
Jhatial, Mussadique Ali
Bokhari, Syed W
Ahsan, Bushra
Ahmad, Usman
author_facet Abbas, Mansoor
Bin Naeem, Sameen
Jhatial, Mussadique Ali
Bokhari, Syed W
Ahsan, Bushra
Ahmad, Usman
author_sort Abbas, Mansoor
collection PubMed
description Acute lymphoblastic leukemia is predominately a childhood disease and around two third of cases are of B-cell phenotype. Cytomegalovirus is an important cause of morbidity and mortality in allogeneic hematopoietic progenitor cell transplant; however, it is rare in patients with B-cell acute lymphoblastic leukemia in non-transplant settings. In this study, we evaluated 72 patients of acute precursor (pre) B-cell acute lymphoblastic leukemia at Shaukat Khanum Memorial Cancer Hospital and Research Center, out of which three were positive for Cytomegalovirus.
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spelling pubmed-98734832023-01-26 Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting Abbas, Mansoor Bin Naeem, Sameen Jhatial, Mussadique Ali Bokhari, Syed W Ahsan, Bushra Ahmad, Usman Cureus Oncology Acute lymphoblastic leukemia is predominately a childhood disease and around two third of cases are of B-cell phenotype. Cytomegalovirus is an important cause of morbidity and mortality in allogeneic hematopoietic progenitor cell transplant; however, it is rare in patients with B-cell acute lymphoblastic leukemia in non-transplant settings. In this study, we evaluated 72 patients of acute precursor (pre) B-cell acute lymphoblastic leukemia at Shaukat Khanum Memorial Cancer Hospital and Research Center, out of which three were positive for Cytomegalovirus. Cureus 2022-12-25 /pmc/articles/PMC9873483/ /pubmed/36712765 http://dx.doi.org/10.7759/cureus.32936 Text en Copyright © 2022, Abbas et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Abbas, Mansoor
Bin Naeem, Sameen
Jhatial, Mussadique Ali
Bokhari, Syed W
Ahsan, Bushra
Ahmad, Usman
Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting
title Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting
title_full Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting
title_fullStr Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting
title_full_unstemmed Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting
title_short Cytomegalovirus Reactivation in Patients With Acute Lymphoblastic Leukemia in Non-transplant Setting
title_sort cytomegalovirus reactivation in patients with acute lymphoblastic leukemia in non-transplant setting
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873483/
https://www.ncbi.nlm.nih.gov/pubmed/36712765
http://dx.doi.org/10.7759/cureus.32936
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