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Hypoxic stress accelerates the propagation of pathological alpha‐synuclein and degeneration of dopaminergic neurons

AIMS: The etiology of Parkinson's disease (PD) is complex and the mechanism is unclear. It has become a top priority to find common factors that induce and affect PD pathology. We explored the key role of hypoxia in promoting the pathological propagation of α‐synuclein (α‐syn) and the progressi...

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Detalles Bibliográficos
Autores principales: Guo, Mengyuan, Liu, Weijin, Luo, Hanjiang, Shao, Qianqian, Li, Yuning, Gu, Yakun, Guan, Yuying, Ma, Wei, Chen, Min, Yang, Hui, Ji, Xunming, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873519/
https://www.ncbi.nlm.nih.gov/pubmed/36514210
http://dx.doi.org/10.1111/cns.14055