Cargando…
Hypoxic stress accelerates the propagation of pathological alpha‐synuclein and degeneration of dopaminergic neurons
AIMS: The etiology of Parkinson's disease (PD) is complex and the mechanism is unclear. It has become a top priority to find common factors that induce and affect PD pathology. We explored the key role of hypoxia in promoting the pathological propagation of α‐synuclein (α‐syn) and the progressi...
Autores principales: | Guo, Mengyuan, Liu, Weijin, Luo, Hanjiang, Shao, Qianqian, Li, Yuning, Gu, Yakun, Guan, Yuying, Ma, Wei, Chen, Min, Yang, Hui, Ji, Xunming, Liu, Jia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873519/ https://www.ncbi.nlm.nih.gov/pubmed/36514210 http://dx.doi.org/10.1111/cns.14055 |
Ejemplares similares
-
Chronic hypoxia leads to cognitive impairment by promoting HIF-2α-mediated ceramide catabolism and alpha-synuclein hyperphosphorylation
por: Li, Gaifen, et al.
Publicado: (2022) -
Intermittent hypoxic conditioning restores neurological dysfunction of mice induced by long‐term hypoxia
por: Li, Gaifen, et al.
Publicado: (2022) -
Proteomic Analysis Reveals That Mitochondria Dominate the Hippocampal Hypoxic Response in Mice
por: Shao, Qianqian, et al.
Publicado: (2022) -
Hypoxia and Alpha-Synuclein: Inextricable Link Underlying the Pathologic Progression of Parkinson's Disease
por: Guo, Mengyuan, et al.
Publicado: (2022) -
Neuroprotective effects and mechanisms of ischemic/hypoxic preconditioning on neurological diseases
por: Liu, Jia, et al.
Publicado: (2021)