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Verteporfin reverses progestin resistance through YAP/TAZ-PI3K-Akt pathway in endometrial carcinoma
Progestin resistance is a problem for patients with endometrial carcinoma (EC) who require conservative treatment with progestin, and its underlying mechanisms remain unclear. YAP and TAZ (YAP/TAZ), downstream transcription coactivators of Hippo pathway, promote viability, metastasis and also drug r...
Autores principales: | Wei, Lina, Ma, Xiaohong, Hou, Yixin, Zhao, Tianyi, Sun, Rui, Qiu, Chunping, Liu, Yao, Qiu, Ziyi, Liu, Zhiming, Jiang, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873621/ https://www.ncbi.nlm.nih.gov/pubmed/36693834 http://dx.doi.org/10.1038/s41420-023-01319-y |
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