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Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations

Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multi...

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Detalles Bibliográficos
Autores principales: Naceur, Ahmed, Hébert, Alain, Romano, Paul, Forget, Benoit, Chilian, Cornelia, Carrier, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873679/
https://www.ncbi.nlm.nih.gov/pubmed/36693824
http://dx.doi.org/10.1038/s41598-023-27376-y
Descripción
Sumario:Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multigroup electron cross sections generation module in NJOY is presented and validated against Lockwood’s calorimetric measurements, EGS-nrc and GEANT-4 for 1–20 MeV unidirectional electron beams. The nuclear-reactor DRAGON-5 solver is upgraded to access the library and solve the Boltzmann–Fokker–Planck (BFP) equation. A variety of heterogeneous radiotherapy and radiosurgery phantom configurations were used for validation purpose. Case studies include a thorax benchmark, that of a typical breast Intra-Operative Radiotherapy and a high-heterogeneity patient-like benchmark. For all beams, [Formula: see text] of the water voxels satisfied the American Association of Physicists in Medicine accuracy criterion for a BFP-MC dose error below [Formula: see text] . At least, [Formula: see text] of adipose, muscle, bone, lung, tumor and breast voxels satisfied the [Formula: see text] criterion. The average BFP-MC relative error was about [Formula: see text] for all voxels, beams and materials combined. By irradiating homogeneous slabs from [Formula: see text] (hydrogen) to [Formula: see text] (einsteinium), we reported performance and defects of the CEPXS mode [US. Sandia National Lab., SAND-89-1685] in ELECTR for the entire periodic table. For all Lockwood’s benchmarks, NJOY-DRAGON dose predictions are within the experimental data precision for [Formula: see text] of voxels.