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Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations

Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multi...

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Autores principales: Naceur, Ahmed, Hébert, Alain, Romano, Paul, Forget, Benoit, Chilian, Cornelia, Carrier, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873679/
https://www.ncbi.nlm.nih.gov/pubmed/36693824
http://dx.doi.org/10.1038/s41598-023-27376-y
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author Naceur, Ahmed
Hébert, Alain
Romano, Paul
Forget, Benoit
Chilian, Cornelia
Carrier, Jean-François
author_facet Naceur, Ahmed
Hébert, Alain
Romano, Paul
Forget, Benoit
Chilian, Cornelia
Carrier, Jean-François
author_sort Naceur, Ahmed
collection PubMed
description Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multigroup electron cross sections generation module in NJOY is presented and validated against Lockwood’s calorimetric measurements, EGS-nrc and GEANT-4 for 1–20 MeV unidirectional electron beams. The nuclear-reactor DRAGON-5 solver is upgraded to access the library and solve the Boltzmann–Fokker–Planck (BFP) equation. A variety of heterogeneous radiotherapy and radiosurgery phantom configurations were used for validation purpose. Case studies include a thorax benchmark, that of a typical breast Intra-Operative Radiotherapy and a high-heterogeneity patient-like benchmark. For all beams, [Formula: see text] of the water voxels satisfied the American Association of Physicists in Medicine accuracy criterion for a BFP-MC dose error below [Formula: see text] . At least, [Formula: see text] of adipose, muscle, bone, lung, tumor and breast voxels satisfied the [Formula: see text] criterion. The average BFP-MC relative error was about [Formula: see text] for all voxels, beams and materials combined. By irradiating homogeneous slabs from [Formula: see text] (hydrogen) to [Formula: see text] (einsteinium), we reported performance and defects of the CEPXS mode [US. Sandia National Lab., SAND-89-1685] in ELECTR for the entire periodic table. For all Lockwood’s benchmarks, NJOY-DRAGON dose predictions are within the experimental data precision for [Formula: see text] of voxels.
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spelling pubmed-98736792023-01-26 Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations Naceur, Ahmed Hébert, Alain Romano, Paul Forget, Benoit Chilian, Cornelia Carrier, Jean-François Sci Rep Article Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multigroup electron cross sections generation module in NJOY is presented and validated against Lockwood’s calorimetric measurements, EGS-nrc and GEANT-4 for 1–20 MeV unidirectional electron beams. The nuclear-reactor DRAGON-5 solver is upgraded to access the library and solve the Boltzmann–Fokker–Planck (BFP) equation. A variety of heterogeneous radiotherapy and radiosurgery phantom configurations were used for validation purpose. Case studies include a thorax benchmark, that of a typical breast Intra-Operative Radiotherapy and a high-heterogeneity patient-like benchmark. For all beams, [Formula: see text] of the water voxels satisfied the American Association of Physicists in Medicine accuracy criterion for a BFP-MC dose error below [Formula: see text] . At least, [Formula: see text] of adipose, muscle, bone, lung, tumor and breast voxels satisfied the [Formula: see text] criterion. The average BFP-MC relative error was about [Formula: see text] for all voxels, beams and materials combined. By irradiating homogeneous slabs from [Formula: see text] (hydrogen) to [Formula: see text] (einsteinium), we reported performance and defects of the CEPXS mode [US. Sandia National Lab., SAND-89-1685] in ELECTR for the entire periodic table. For all Lockwood’s benchmarks, NJOY-DRAGON dose predictions are within the experimental data precision for [Formula: see text] of voxels. Nature Publishing Group UK 2023-01-24 /pmc/articles/PMC9873679/ /pubmed/36693824 http://dx.doi.org/10.1038/s41598-023-27376-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Naceur, Ahmed
Hébert, Alain
Romano, Paul
Forget, Benoit
Chilian, Cornelia
Carrier, Jean-François
Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
title Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
title_full Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
title_fullStr Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
title_full_unstemmed Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
title_short Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
title_sort feasibility of a multigroup boltzmann–fokker–planck solution for electron beam dose calculations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873679/
https://www.ncbi.nlm.nih.gov/pubmed/36693824
http://dx.doi.org/10.1038/s41598-023-27376-y
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