Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors

PD-1 is an inhibitory receptor in T cells, and antibodies that block its interaction with ligands augment anti-tumor immune responses. The clinical potential of these agents is limited by the fact that half of all patients develop immune-related adverse events (irAEs). To generate insights into the...

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Detalles Bibliográficos
Autores principales: Bukhari, Shoiab, Henick, Brian S., Winchester, Robert J., Lerrer, Shalom, Adam, Kieran, Gartshteyn, Yevgeniya, Maniar, Rohan, Lin, Ziyan, Khodadadi-Jamayran, Alireza, Tsirigos, Aristotelis, Salvatore, Mary M., Lagos, Galina G., Reiner, Steven L., Dallos, Matthew C., Mathew, Matthen, Rizvi, Naiyer A., Mor, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873824/
https://www.ncbi.nlm.nih.gov/pubmed/36513074
http://dx.doi.org/10.1016/j.xcrm.2022.100868

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