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Chromosome territory reorganization through artificial chromosome fusion is compatible with cell fate determination and mouse development
Chromosomes occupy discrete spaces in the interphase cell nucleus, called chromosome territory. The structural and functional relevance of chromosome territory remains elusive. We fused chromosome 15 and 17 in mouse haploid embryonic stem cells (haESCs), resulting in distinct changes of territories...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Nature Singapore
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873915/ https://www.ncbi.nlm.nih.gov/pubmed/36693846 http://dx.doi.org/10.1038/s41421-022-00511-1 |