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Reduction of amputations of frostbitten limbs by treatment using microwave rewarming

Drug treatment of limb frostbite injuries is complicated due to the poor delivery of medications to affected tissues. External rewarming of the frostbitten area is risky and does not always result in positive outcomes because the dilatation of superficial vessels with constricted deep vessels can le...

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Autores principales: Dunaevskiy, Grigory, Gavrilin, Eugene, Pomytkin, Alexander, Sorokin, Roman, Kuznetsov, Artem, Antipov, Vladimir, Nechaev, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873917/
https://www.ncbi.nlm.nih.gov/pubmed/36693895
http://dx.doi.org/10.1038/s41598-023-28535-x
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author Dunaevskiy, Grigory
Gavrilin, Eugene
Pomytkin, Alexander
Sorokin, Roman
Kuznetsov, Artem
Antipov, Vladimir
Nechaev, Aleksander
author_facet Dunaevskiy, Grigory
Gavrilin, Eugene
Pomytkin, Alexander
Sorokin, Roman
Kuznetsov, Artem
Antipov, Vladimir
Nechaev, Aleksander
author_sort Dunaevskiy, Grigory
collection PubMed
description Drug treatment of limb frostbite injuries is complicated due to the poor delivery of medications to affected tissues. External rewarming of the frostbitten area is risky and does not always result in positive outcomes because the dilatation of superficial vessels with constricted deep vessels can lead to irreversible damage, necrosis, and amputation. One of the techniques to restore perfusion of deep vessels in an affected extremity is rewarming with low-power microwave radiation in a specially designed metal chamber. Below are findings following treatment of 14 volunteers with this technique in 2 Tomsk hospitals during winters of 2018–2021. It is demonstrated that timely, i.e. in the early reactive period, application of microwave radiation and appropriate supportive drug treatment results in positive amputation-free outcomes. The key requirement is prompt thermal insulation of the trauma and no prior exposure to external heat sources.
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spelling pubmed-98739172023-01-26 Reduction of amputations of frostbitten limbs by treatment using microwave rewarming Dunaevskiy, Grigory Gavrilin, Eugene Pomytkin, Alexander Sorokin, Roman Kuznetsov, Artem Antipov, Vladimir Nechaev, Aleksander Sci Rep Article Drug treatment of limb frostbite injuries is complicated due to the poor delivery of medications to affected tissues. External rewarming of the frostbitten area is risky and does not always result in positive outcomes because the dilatation of superficial vessels with constricted deep vessels can lead to irreversible damage, necrosis, and amputation. One of the techniques to restore perfusion of deep vessels in an affected extremity is rewarming with low-power microwave radiation in a specially designed metal chamber. Below are findings following treatment of 14 volunteers with this technique in 2 Tomsk hospitals during winters of 2018–2021. It is demonstrated that timely, i.e. in the early reactive period, application of microwave radiation and appropriate supportive drug treatment results in positive amputation-free outcomes. The key requirement is prompt thermal insulation of the trauma and no prior exposure to external heat sources. Nature Publishing Group UK 2023-01-24 /pmc/articles/PMC9873917/ /pubmed/36693895 http://dx.doi.org/10.1038/s41598-023-28535-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Dunaevskiy, Grigory
Gavrilin, Eugene
Pomytkin, Alexander
Sorokin, Roman
Kuznetsov, Artem
Antipov, Vladimir
Nechaev, Aleksander
Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
title Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
title_full Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
title_fullStr Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
title_full_unstemmed Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
title_short Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
title_sort reduction of amputations of frostbitten limbs by treatment using microwave rewarming
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873917/
https://www.ncbi.nlm.nih.gov/pubmed/36693895
http://dx.doi.org/10.1038/s41598-023-28535-x
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