Cargando…
Reduction of amputations of frostbitten limbs by treatment using microwave rewarming
Drug treatment of limb frostbite injuries is complicated due to the poor delivery of medications to affected tissues. External rewarming of the frostbitten area is risky and does not always result in positive outcomes because the dilatation of superficial vessels with constricted deep vessels can le...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873917/ https://www.ncbi.nlm.nih.gov/pubmed/36693895 http://dx.doi.org/10.1038/s41598-023-28535-x |
_version_ | 1784877687175643136 |
---|---|
author | Dunaevskiy, Grigory Gavrilin, Eugene Pomytkin, Alexander Sorokin, Roman Kuznetsov, Artem Antipov, Vladimir Nechaev, Aleksander |
author_facet | Dunaevskiy, Grigory Gavrilin, Eugene Pomytkin, Alexander Sorokin, Roman Kuznetsov, Artem Antipov, Vladimir Nechaev, Aleksander |
author_sort | Dunaevskiy, Grigory |
collection | PubMed |
description | Drug treatment of limb frostbite injuries is complicated due to the poor delivery of medications to affected tissues. External rewarming of the frostbitten area is risky and does not always result in positive outcomes because the dilatation of superficial vessels with constricted deep vessels can lead to irreversible damage, necrosis, and amputation. One of the techniques to restore perfusion of deep vessels in an affected extremity is rewarming with low-power microwave radiation in a specially designed metal chamber. Below are findings following treatment of 14 volunteers with this technique in 2 Tomsk hospitals during winters of 2018–2021. It is demonstrated that timely, i.e. in the early reactive period, application of microwave radiation and appropriate supportive drug treatment results in positive amputation-free outcomes. The key requirement is prompt thermal insulation of the trauma and no prior exposure to external heat sources. |
format | Online Article Text |
id | pubmed-9873917 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-98739172023-01-26 Reduction of amputations of frostbitten limbs by treatment using microwave rewarming Dunaevskiy, Grigory Gavrilin, Eugene Pomytkin, Alexander Sorokin, Roman Kuznetsov, Artem Antipov, Vladimir Nechaev, Aleksander Sci Rep Article Drug treatment of limb frostbite injuries is complicated due to the poor delivery of medications to affected tissues. External rewarming of the frostbitten area is risky and does not always result in positive outcomes because the dilatation of superficial vessels with constricted deep vessels can lead to irreversible damage, necrosis, and amputation. One of the techniques to restore perfusion of deep vessels in an affected extremity is rewarming with low-power microwave radiation in a specially designed metal chamber. Below are findings following treatment of 14 volunteers with this technique in 2 Tomsk hospitals during winters of 2018–2021. It is demonstrated that timely, i.e. in the early reactive period, application of microwave radiation and appropriate supportive drug treatment results in positive amputation-free outcomes. The key requirement is prompt thermal insulation of the trauma and no prior exposure to external heat sources. Nature Publishing Group UK 2023-01-24 /pmc/articles/PMC9873917/ /pubmed/36693895 http://dx.doi.org/10.1038/s41598-023-28535-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Dunaevskiy, Grigory Gavrilin, Eugene Pomytkin, Alexander Sorokin, Roman Kuznetsov, Artem Antipov, Vladimir Nechaev, Aleksander Reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
title | Reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
title_full | Reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
title_fullStr | Reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
title_full_unstemmed | Reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
title_short | Reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
title_sort | reduction of amputations of frostbitten limbs by treatment using microwave rewarming |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873917/ https://www.ncbi.nlm.nih.gov/pubmed/36693895 http://dx.doi.org/10.1038/s41598-023-28535-x |
work_keys_str_mv | AT dunaevskiygrigory reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming AT gavrilineugene reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming AT pomytkinalexander reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming AT sorokinroman reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming AT kuznetsovartem reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming AT antipovvladimir reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming AT nechaevaleksander reductionofamputationsoffrostbittenlimbsbytreatmentusingmicrowaverewarming |