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Element- and enantiomer-selective visualization of molecular motion in real-time

Ultrafast optical-domain spectroscopies allow to monitor in real time the motion of nuclei in molecules. Achieving element-selectivity had to await the advent of time resolved X-ray spectroscopy, which is now commonly carried at X-ray free electron lasers. However, detecting light element that are c...

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Autores principales: Mincigrucci, R., Rouxel, J. R., Rossi, B., Principi, E., Bottari, C., Catalini, S., Pelli-Cresi, J. S., Fainozzi, D., Foglia, L., Simoncig, A., Matruglio, A., Kurdi, G., Capotondi, F., Pedersoli, E., Perucchi, A., Piccirilli, F., Gessini, A., Giarola, M., Mariotto, G., Oppermann, M., Mukamel, S., Bencivenga, F., Chergui, M., Masciovecchio, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873934/
https://www.ncbi.nlm.nih.gov/pubmed/36693825
http://dx.doi.org/10.1038/s41467-023-36047-5
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author Mincigrucci, R.
Rouxel, J. R.
Rossi, B.
Principi, E.
Bottari, C.
Catalini, S.
Pelli-Cresi, J. S.
Fainozzi, D.
Foglia, L.
Simoncig, A.
Matruglio, A.
Kurdi, G.
Capotondi, F.
Pedersoli, E.
Perucchi, A.
Piccirilli, F.
Gessini, A.
Giarola, M.
Mariotto, G.
Oppermann, M.
Mukamel, S.
Bencivenga, F.
Chergui, M.
Masciovecchio, C.
author_facet Mincigrucci, R.
Rouxel, J. R.
Rossi, B.
Principi, E.
Bottari, C.
Catalini, S.
Pelli-Cresi, J. S.
Fainozzi, D.
Foglia, L.
Simoncig, A.
Matruglio, A.
Kurdi, G.
Capotondi, F.
Pedersoli, E.
Perucchi, A.
Piccirilli, F.
Gessini, A.
Giarola, M.
Mariotto, G.
Oppermann, M.
Mukamel, S.
Bencivenga, F.
Chergui, M.
Masciovecchio, C.
author_sort Mincigrucci, R.
collection PubMed
description Ultrafast optical-domain spectroscopies allow to monitor in real time the motion of nuclei in molecules. Achieving element-selectivity had to await the advent of time resolved X-ray spectroscopy, which is now commonly carried at X-ray free electron lasers. However, detecting light element that are commonly encountered in organic molecules, remained elusive due to the need to work under vacuum. Here, we present an impulsive stimulated Raman scattering (ISRS) pump/carbon K-edge absorption probe investigation, which allowed observation of the low-frequency vibrational modes involving specific selected carbon atoms in the Ibuprofen RS dimer. Remarkably, by controlling the probe light polarization we can preferentially access the enantiomer of the dimer to which the carbon atoms belong.
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spelling pubmed-98739342023-01-26 Element- and enantiomer-selective visualization of molecular motion in real-time Mincigrucci, R. Rouxel, J. R. Rossi, B. Principi, E. Bottari, C. Catalini, S. Pelli-Cresi, J. S. Fainozzi, D. Foglia, L. Simoncig, A. Matruglio, A. Kurdi, G. Capotondi, F. Pedersoli, E. Perucchi, A. Piccirilli, F. Gessini, A. Giarola, M. Mariotto, G. Oppermann, M. Mukamel, S. Bencivenga, F. Chergui, M. Masciovecchio, C. Nat Commun Article Ultrafast optical-domain spectroscopies allow to monitor in real time the motion of nuclei in molecules. Achieving element-selectivity had to await the advent of time resolved X-ray spectroscopy, which is now commonly carried at X-ray free electron lasers. However, detecting light element that are commonly encountered in organic molecules, remained elusive due to the need to work under vacuum. Here, we present an impulsive stimulated Raman scattering (ISRS) pump/carbon K-edge absorption probe investigation, which allowed observation of the low-frequency vibrational modes involving specific selected carbon atoms in the Ibuprofen RS dimer. Remarkably, by controlling the probe light polarization we can preferentially access the enantiomer of the dimer to which the carbon atoms belong. Nature Publishing Group UK 2023-01-24 /pmc/articles/PMC9873934/ /pubmed/36693825 http://dx.doi.org/10.1038/s41467-023-36047-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mincigrucci, R.
Rouxel, J. R.
Rossi, B.
Principi, E.
Bottari, C.
Catalini, S.
Pelli-Cresi, J. S.
Fainozzi, D.
Foglia, L.
Simoncig, A.
Matruglio, A.
Kurdi, G.
Capotondi, F.
Pedersoli, E.
Perucchi, A.
Piccirilli, F.
Gessini, A.
Giarola, M.
Mariotto, G.
Oppermann, M.
Mukamel, S.
Bencivenga, F.
Chergui, M.
Masciovecchio, C.
Element- and enantiomer-selective visualization of molecular motion in real-time
title Element- and enantiomer-selective visualization of molecular motion in real-time
title_full Element- and enantiomer-selective visualization of molecular motion in real-time
title_fullStr Element- and enantiomer-selective visualization of molecular motion in real-time
title_full_unstemmed Element- and enantiomer-selective visualization of molecular motion in real-time
title_short Element- and enantiomer-selective visualization of molecular motion in real-time
title_sort element- and enantiomer-selective visualization of molecular motion in real-time
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873934/
https://www.ncbi.nlm.nih.gov/pubmed/36693825
http://dx.doi.org/10.1038/s41467-023-36047-5
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