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Illuminating the mechanism of IL-6-mediated immunotherapy resistance
Huseni et al. report that IL-6-STAT3 signaling negatively impacts the anti-tumor function of cytotoxic T cells. Targeting IL-6 signaling may enhance tumor responses to immune checkpoint blockade therapy.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873941/ https://www.ncbi.nlm.nih.gov/pubmed/36652910 http://dx.doi.org/10.1016/j.xcrm.2022.100901 |