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Integrated untargeted and targeted metabolomics to reveal therapeutic effect and mechanism of Alpiniae oxyphyllae fructus on Alzheimer’s disease in APP/PS1 mice

Introduction: Alpiniae oxyphyllae Fructus (AOF) has been abundantly utilized for the treatment of diarrhea, dyspepsia, kidney asthenia, and abdominal pain in China. AOF is effective for treating AD in clinical trials, but its exact mode of action is yet unknown. Methods: In this study, metabolomics...

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Detalles Bibliográficos
Autores principales:	Zhou, Shengnan, Liu, Liwei, Zhang, Yuanyuan, Zhang, Zhibo, Li, Hanbing, Fan, Feng, He, Jiuming, Kang, Jian, Zuo, Lihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873993/ https://www.ncbi.nlm.nih.gov/pubmed/36712678 http://dx.doi.org/10.3389/fphar.2022.1104954

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