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Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines
Cellular utilization of available energy flows to drive a multitude of forms of cellular “work” is a major biological constraint. Cells steer metabolism to address changing phenotypic states but little is known as to how bioenergetics couples to the richness of processes in a cell as a whole. Here,...
Autores principales: | Sevrin, Thomas, Strasser, Lisa, Ternet, Camille, Junk, Philipp, Caffarini, Miriam, Prins, Stella, D’Arcy, Cian, Catozzi, Simona, Oliviero, Giorgio, Wynne, Kieran, Kiel, Christina, Luthert, Philip J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874014/ https://www.ncbi.nlm.nih.gov/pubmed/36711246 http://dx.doi.org/10.1016/j.isci.2023.105931 |
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