Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients

Transcription factor programs mediating the immune response to coronavirus disease 2019 (COVID-19) are not fully understood. Capturing active transcription initiation from cis-regulatory elements such as enhancers and promoters by capped small RNA sequencing (csRNA-seq), in contrast to capturing ste...

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Detalles Bibliográficos
Autores principales: Lam, Michael Tun Yin, Duttke, Sascha H., Odish, Mazen F., Le, Hiep D., Hansen, Emily A., Nguyen, Celina T., Trescott, Samantha, Kim, Roy, Deota, Shaunak, Chang, Max W., Patel, Arjun, Hepokoski, Mark, Alotaibi, Mona, Rolfsen, Mark, Perofsky, Katherine, Warden, Anna S., Foley, Jennifer, Ramirez, Sydney I., Dan, Jennifer M., Abbott, Robert K., Crotty, Shane, Crotty Alexander, Laura E., Malhotra, Atul, Panda, Satchidananda, Benner, Christopher W., Coufal, Nicole G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874047/
https://www.ncbi.nlm.nih.gov/pubmed/36758547
http://dx.doi.org/10.1016/j.xcrm.2023.100935

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