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Assessing the Evidence for Causal Associations Between Body Mass Index, C-Reactive Protein, Depression, and Reported Trauma Using Mendelian Randomization
BACKGROUND: Traumatic experiences are described as the strongest predictors of major depressive disorder (MDD), with inflammation potentially mediating the association between trauma and symptom onset. However, several studies indicate that body mass index (BMI) exerts a large confounding effect on...
Autores principales: | Palmos, Alish B., Hübel, Christopher, Lim, Kai Xiang, Hunjan, Avina K., Coleman, Jonathan R.I., Breen, Gerome |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874165/ https://www.ncbi.nlm.nih.gov/pubmed/36712567 http://dx.doi.org/10.1016/j.bpsgos.2022.01.003 |
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