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Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis

INTRODUCTION: Previous studies suggest that monocytes are an important contributor to tuberculosis (TB)-specific immune signatures in blood. METHODS: Here, we carried out comprehensive single-cell profiling of monocytes in paired blood samples of active TB (ATB) patients at diagnosis and mid-treatme...

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Detalles Bibliográficos
Autores principales: Hillman, Hannah, Khan, Nabeela, Singhania, Akul, Dubelko, Paige, Soldevila, Ferran, Tippalagama, Rashmi, DeSilva, Aruna D., Gunasena, Bandu, Perera, Judy, Scriba, Thomas J., Ontong, Cynthia, Fisher, Michelle, Luabeya, Angelique, Taplitz, Randy, Seumois, Gregory, Vijayanand, Pandurangan, Hedrick, Catherine C., Peters, Bjoern, Burel, Julie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874319/
https://www.ncbi.nlm.nih.gov/pubmed/36713384
http://dx.doi.org/10.3389/fimmu.2022.1087010

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