CK2β-regulated signaling controls B cell differentiation and function

Serine-Threonine kinase CK2 supports malignant B-lymphocyte growth but its role in B-cell development and activation is largely unknown. Here, we describe the first B-cell specific knockout (KO) mouse model of the β regulatory subunit of CK2. CK2β(KO) mice present an increase in marginal zone (MZ) a...

Descripción completa

Detalles Bibliográficos
Autores principales: Quotti Tubi, Laura, Mandato, Elisa, Canovas Nunes, Sara, Arjomand, Arash, Zaffino, Fortunato, Manni, Sabrina, Casellato, Alessandro, Macaccaro, Paolo, Vitulo, Nicola, Zumerle, Sara, Filhol, Odile, Boldyreff, Brigitte, Siebel, Christian W., Viola, Antonella, Valle, Giorgio, Mainoldi, Federica, Casola, Stefano, Cancila, Valeria, Gulino, Alessandro, Tripodo, Claudio, Pizzi, Marco, Dei Tos, Angelo Paolo, Trentin, Livio, Semenzato, Gianpietro, Piazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874936/
https://www.ncbi.nlm.nih.gov/pubmed/36713383
http://dx.doi.org/10.3389/fimmu.2022.959138

Ejemplares similares

Ejemplares similares