A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction

SUMMARY: In this study, we herein describe a 47-year-old Japanese woman who manifested inheritable non-alcoholic steatohepatitis (NASH) and severe dyslipidemia. Interestingly, her NASH progression was ameliorated by treatment with a sodium–glucose co-transporter 2 (SGLT2) inhibitor. This inheritabil...

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Detalles Bibliográficos
Autores principales: Nakajima, Rikako, Sekiya, Motohiro, Furuta, Yasuhisa, Miyamoto, Takafumi, Sato, Masashi, Fukuda, Kuniaki, Hattori, Keiichiro, Suehara, Yasuhito, Sakata-Yanagimoto, Mamiko, Chiba, Shigeru, Okajima, Yuka, Matsuzaka, Takashi, Takase, Satoru, Takanashi, Mikio, Okazaki, Hiroaki, Takashima, Yusuke, Yuhara, Mikiko, Mitani, Yuta, Matsumoto, Nako, Murayama, Yuki, Ohyama Osawa, Mariko, Ohuchi, Nami, Yamazaki, Daichi, Mori, Sayuri, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Suzuki, Hiroaki, Shimano, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Insight into Disease Pathogenesis or Mechanism of Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874953/
https://www.ncbi.nlm.nih.gov/pubmed/36571472
http://dx.doi.org/10.1530/EDM-22-0368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874953/
https://www.ncbi.nlm.nih.gov/pubmed/36571472
http://dx.doi.org/10.1530/EDM-22-0368

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