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Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxia
A central response to insufficient cerebral oxygen delivery is a profound reprograming of metabolism, which is mainly regulated by the Hypoxia Inducible Factor (HIF). Among other responses, HIF induces the expression of the atypical mitochondrial subunit NDUFA4L2. Surprisingly, NDUFA4L2 is constitut...
Autores principales: | Mesa-Ciller, Claudia, Turiel, Guillermo, Guajardo-Grence, Andrea, Lopez-Rodriguez, Ana Belen, Egea, Javier, De Bock, Katrien, Aragonés, Julián, Urrutia, Andrés A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875353/ https://www.ncbi.nlm.nih.gov/pubmed/35929074 http://dx.doi.org/10.1177/0271678X221118236 |
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