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Transfer of mesenchymal stem cell mitochondria to CD4(+) T cells contributes to repress Th1 differentiation by downregulating T-bet expression

BACKGROUND: Mesenchymal stem/stromal cells (MSCs) are multipotent cells with strong tissue repair and immunomodulatory properties. Due to their ability to repress pathogenic immune responses, and in particular T cell responses, they show therapeutic potential for the treatment of autoimmune diseases...

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Detalles Bibliográficos
Autores principales:	Akhter, Waseem, Nakhle, Jean, Vaillant, Loïc, Garcin, Geneviève, Le Saout, Cécile, Simon, Matthieu, Crozet, Carole, Djouad, Farida, Jorgensen, Christian, Vignais, Marie-Luce, Hernandez, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875419/ https://www.ncbi.nlm.nih.gov/pubmed/36694226 http://dx.doi.org/10.1186/s13287-022-03219-x

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