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TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability

BACKGROUND: Metabolic reprogramming is a hallmark of various cancers. Targeting metabolic processes is a very attractive treatment for cancer. Renal cell carcinoma (RCC) is a type of metabolic disease, and the lipidomic profile of RCC is significantly altered compared with that of healthy tissue. Ho...

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Detalles Bibliográficos
Autores principales: Chen, Xintian, Yong, Hongmei, Chen, Miaolei, Deng, Chuyin, Wang, Pengfei, Chu, Sufang, Li, Minle, Hou, Pingfu, Zheng, Junnian, Li, Zhongwei, Bai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875457/
https://www.ncbi.nlm.nih.gov/pubmed/36694250
http://dx.doi.org/10.1186/s13046-022-02583-z