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Adipokine chemerin overexpression in trophoblasts leads to dyslipidemia in pregnant mice: implications for preeclampsia

BACKGROUND: The adipokine chemerin regulates adipogenesis and the metabolic function of both adipocytes and liver. Chemerin is elevated in preeclamptic women, and overexpression of chemerin in placental trophoblasts induces preeclampsia-like symptoms in mice. Preeclampsia is known to be accompanied...

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Detalles Bibliográficos
Autores principales: Tan, Lunbo, Ouyang, Zijun, Chen, Zhilong, Sun, Fen, Guo, Haichun, Wang, Feng, Mulder, Monique, Sun, Yuan, Lu, Xifeng, Zhang, Jian V., Danser, A. H. Jan, Verdonk, Koen, Fan, Xiujun, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875463/
https://www.ncbi.nlm.nih.gov/pubmed/36698175
http://dx.doi.org/10.1186/s12944-023-01777-4