Magnetofection of miR-21 promoted by electromagnetic field and iron oxide nanoparticles via the p38 MAPK pathway contributes to osteogenesis and angiogenesis for intervertebral fusion

BACKGROUND: Magnetofection-mediated gene delivery shows great therapeutic potential through the regulation of the direction and degree of differentiation. Lumbar degenerative disc disease (DDD) is a serious global orthopaedic problem. However, even though intervertebral fusion is the gold standard f...

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Detalles Bibliográficos
Autores principales: Wang, Tianqi, Zhao, Hongqi, Jing, Shaoze, Fan, Yang, Sheng, Gaohong, Ding, Qing, Liu, Chaoxu, Wu, Hua, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875474/
https://www.ncbi.nlm.nih.gov/pubmed/36694219
http://dx.doi.org/10.1186/s12951-023-01789-3

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