Tumor microenvironment in ovarian cancer peritoneal metastasis

Ovarian cancer (OC) is one of the most common gynecological malignancies with high morbidity and mortality. The peritoneum is one of the most common metastatic sites in ovarian cancer, involving large amounts of ascites. However, its mechanism is unclear. The peritoneal microenvironment composed of...

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Autores principales: Mei, Shuangshuang, Chen, Xing, Wang, Kai, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875479/
https://www.ncbi.nlm.nih.gov/pubmed/36698173
http://dx.doi.org/10.1186/s12935-023-02854-5
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author Mei, Shuangshuang
Chen, Xing
Wang, Kai
Chen, Yuxin
author_facet Mei, Shuangshuang
Chen, Xing
Wang, Kai
Chen, Yuxin
author_sort Mei, Shuangshuang
collection PubMed
description Ovarian cancer (OC) is one of the most common gynecological malignancies with high morbidity and mortality. The peritoneum is one of the most common metastatic sites in ovarian cancer, involving large amounts of ascites. However, its mechanism is unclear. The peritoneal microenvironment composed of peritoneal effusion and peritoneum creates favorable conditions for ovarian cancer progression and metastasis. Here, we reviewed the peritoneal metastasis patterns and molecular mechanisms of ovarian cancer, as well as major components of the peritoneal microenvironment, peritoneal effusion, and immune microenvironment, and investigated the relationship between the peritoneal microenvironment and ovarian cancer metastasis.
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spelling pubmed-98754792023-01-26 Tumor microenvironment in ovarian cancer peritoneal metastasis Mei, Shuangshuang Chen, Xing Wang, Kai Chen, Yuxin Cancer Cell Int Review Ovarian cancer (OC) is one of the most common gynecological malignancies with high morbidity and mortality. The peritoneum is one of the most common metastatic sites in ovarian cancer, involving large amounts of ascites. However, its mechanism is unclear. The peritoneal microenvironment composed of peritoneal effusion and peritoneum creates favorable conditions for ovarian cancer progression and metastasis. Here, we reviewed the peritoneal metastasis patterns and molecular mechanisms of ovarian cancer, as well as major components of the peritoneal microenvironment, peritoneal effusion, and immune microenvironment, and investigated the relationship between the peritoneal microenvironment and ovarian cancer metastasis. BioMed Central 2023-01-25 /pmc/articles/PMC9875479/ /pubmed/36698173 http://dx.doi.org/10.1186/s12935-023-02854-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Mei, Shuangshuang
Chen, Xing
Wang, Kai
Chen, Yuxin
Tumor microenvironment in ovarian cancer peritoneal metastasis
title Tumor microenvironment in ovarian cancer peritoneal metastasis
title_full Tumor microenvironment in ovarian cancer peritoneal metastasis
title_fullStr Tumor microenvironment in ovarian cancer peritoneal metastasis
title_full_unstemmed Tumor microenvironment in ovarian cancer peritoneal metastasis
title_short Tumor microenvironment in ovarian cancer peritoneal metastasis
title_sort tumor microenvironment in ovarian cancer peritoneal metastasis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875479/
https://www.ncbi.nlm.nih.gov/pubmed/36698173
http://dx.doi.org/10.1186/s12935-023-02854-5
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AT wangkai tumormicroenvironmentinovariancancerperitonealmetastasis
AT chenyuxin tumormicroenvironmentinovariancancerperitonealmetastasis

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