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Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis
BACKGROUND: Chronic obstructive pulmonary disease (COPD) varies significantly in symptomatic and physiologic presentation. Identifying disease subtypes from molecular data, collected from easily accessible blood samples, can help stratify patients and guide disease management and treatment. METHODS:...
Autores principales: | Buschur, Kristina L., Riley, Craig, Saferali, Aabida, Castaldi, Peter, Zhang, Grace, Aguet, Francois, Ardlie, Kristin G., Durda, Peter, Craig Johnson, W., Kasela, Silva, Liu, Yongmei, Manichaikul, Ani, Rich, Stephen S., Rotter, Jerome I., Smith, Josh, Taylor, Kent D., Tracy, Russell P., Lappalainen, Tuuli, Graham Barr, R., Sciurba, Frank, Hersh, Craig P., Benos, Panayiotis V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875487/ https://www.ncbi.nlm.nih.gov/pubmed/36698131 http://dx.doi.org/10.1186/s12931-023-02316-6 |
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