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Epidemiology of pediatric sarcoma in Iran

BACKGROUND: Pediatric sarcomas are divided into two major groups of soft‐tissue sarcomas (STSs) and malignant bone tumors (MBTs). AIMS: The aim of the present study was to determine the incidence and survival rate of STSs and MBTs in the Iranian population based on diagnosis date, gender, age, and h...

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Autores principales: Azizmohammad Looha, Mehdi, Akbari, Atieh, Akbari, Mohammad Esmaeil, Zarean, Elaheh, Mehrvar, Narjes, Khodakarim, Soheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875610/
https://www.ncbi.nlm.nih.gov/pubmed/35761437
http://dx.doi.org/10.1002/cnr2.1660
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author Azizmohammad Looha, Mehdi
Akbari, Atieh
Akbari, Mohammad Esmaeil
Zarean, Elaheh
Mehrvar, Narjes
Khodakarim, Soheila
author_facet Azizmohammad Looha, Mehdi
Akbari, Atieh
Akbari, Mohammad Esmaeil
Zarean, Elaheh
Mehrvar, Narjes
Khodakarim, Soheila
author_sort Azizmohammad Looha, Mehdi
collection PubMed
description BACKGROUND: Pediatric sarcomas are divided into two major groups of soft‐tissue sarcomas (STSs) and malignant bone tumors (MBTs). AIMS: The aim of the present study was to determine the incidence and survival rate of STSs and MBTs in the Iranian population based on diagnosis date, gender, age, and histological types. METHODS AND RESULTS: Data was retrieved from Iran National Cancer Registry between 2008 and 2015. The dataset was classified according to the third edition of the International Classification of Childhood Cancer. The survival information was merely available for 291 (21% of total data), including 142 (49%) MBTs and 149 (51%) STSs. The age‐standardized incidence rates (ASIRs) and five‐year survival rates were calculated. CONCLUSION: The present study is the first comprehensive study of pediatric sarcomas in Iran, in which a lower incidence and survival rate of MBTs and STSs compared with high‐income countries were found. However, the survival rates of these malignancies were higher in high‐income countries compared to Iran. This study showed the need to improve the quantity and quality of the population‐based registry in Iran for acquiring progress in the prevention and control of sarcomas.
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spelling pubmed-98756102023-01-25 Epidemiology of pediatric sarcoma in Iran Azizmohammad Looha, Mehdi Akbari, Atieh Akbari, Mohammad Esmaeil Zarean, Elaheh Mehrvar, Narjes Khodakarim, Soheila Cancer Rep (Hoboken) Original Articles BACKGROUND: Pediatric sarcomas are divided into two major groups of soft‐tissue sarcomas (STSs) and malignant bone tumors (MBTs). AIMS: The aim of the present study was to determine the incidence and survival rate of STSs and MBTs in the Iranian population based on diagnosis date, gender, age, and histological types. METHODS AND RESULTS: Data was retrieved from Iran National Cancer Registry between 2008 and 2015. The dataset was classified according to the third edition of the International Classification of Childhood Cancer. The survival information was merely available for 291 (21% of total data), including 142 (49%) MBTs and 149 (51%) STSs. The age‐standardized incidence rates (ASIRs) and five‐year survival rates were calculated. CONCLUSION: The present study is the first comprehensive study of pediatric sarcomas in Iran, in which a lower incidence and survival rate of MBTs and STSs compared with high‐income countries were found. However, the survival rates of these malignancies were higher in high‐income countries compared to Iran. This study showed the need to improve the quantity and quality of the population‐based registry in Iran for acquiring progress in the prevention and control of sarcomas. John Wiley and Sons Inc. 2022-06-27 /pmc/articles/PMC9875610/ /pubmed/35761437 http://dx.doi.org/10.1002/cnr2.1660 Text en © 2022 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Azizmohammad Looha, Mehdi
Akbari, Atieh
Akbari, Mohammad Esmaeil
Zarean, Elaheh
Mehrvar, Narjes
Khodakarim, Soheila
Epidemiology of pediatric sarcoma in Iran
title Epidemiology of pediatric sarcoma in Iran
title_full Epidemiology of pediatric sarcoma in Iran
title_fullStr Epidemiology of pediatric sarcoma in Iran
title_full_unstemmed Epidemiology of pediatric sarcoma in Iran
title_short Epidemiology of pediatric sarcoma in Iran
title_sort epidemiology of pediatric sarcoma in iran
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875610/
https://www.ncbi.nlm.nih.gov/pubmed/35761437
http://dx.doi.org/10.1002/cnr2.1660
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