Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023)

Smart Supramolecular Peptides In article number 2203351, Lei Wang, Hao Wang, Bo Hu, and co‐workers report the formulation of a smart supramolecular peptide (SSP) eye drop for diabetic retinopathy treatment that is effective via specifically identifying and capturing Semaphorin4D (Sema 4D), a strongl...

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Detalles Bibliográficos
Autores principales: Li, Ya‐Nan, Liang, Hong‐Wen, Zhang, Chun‐Lin, Qiu, Yan‐Mei, Wang, David, Wang, Hai‐Ling, Chen, An‐Qi, Hong, Can‐Dong, Wang, Lei, Wang, Hao, Hu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875679/
http://dx.doi.org/10.1002/advs.202370012
Descripción
Sumario:Smart Supramolecular Peptides In article number 2203351, Lei Wang, Hao Wang, Bo Hu, and co‐workers report the formulation of a smart supramolecular peptide (SSP) eye drop for diabetic retinopathy treatment that is effective via specifically identifying and capturing Semaphorin4D (Sema 4D), a strongly pro‐angiogenesis and exudates factor. The combination of SSP eye drop and anti‐vascular endothelial growth factor (VEGF) injection showed approximately two times better therapeutic effect over anti‐VEGF treatment alone. This work provides an alternative and effective method for noninvasive treatment for diabetic retinopathy. [Image: see text]

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