Cargando…
Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023)
Smart Supramolecular Peptides In article number 2203351, Lei Wang, Hao Wang, Bo Hu, and co‐workers report the formulation of a smart supramolecular peptide (SSP) eye drop for diabetic retinopathy treatment that is effective via specifically identifying and capturing Semaphorin4D (Sema 4D), a strongl...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875679/ http://dx.doi.org/10.1002/advs.202370012 |
| _version_ | 1784878012736471040 |
|---|---|
| author | Li, Ya‐Nan Liang, Hong‐Wen Zhang, Chun‐Lin Qiu, Yan‐Mei Wang, David Wang, Hai‐Ling Chen, An‐Qi Hong, Can‐Dong Wang, Lei Wang, Hao Hu, Bo |
| author_facet | Li, Ya‐Nan Liang, Hong‐Wen Zhang, Chun‐Lin Qiu, Yan‐Mei Wang, David Wang, Hai‐Ling Chen, An‐Qi Hong, Can‐Dong Wang, Lei Wang, Hao Hu, Bo |
| author_sort | Li, Ya‐Nan |
| collection | PubMed |
| description | Smart Supramolecular Peptides In article number 2203351, Lei Wang, Hao Wang, Bo Hu, and co‐workers report the formulation of a smart supramolecular peptide (SSP) eye drop for diabetic retinopathy treatment that is effective via specifically identifying and capturing Semaphorin4D (Sema 4D), a strongly pro‐angiogenesis and exudates factor. The combination of SSP eye drop and anti‐vascular endothelial growth factor (VEGF) injection showed approximately two times better therapeutic effect over anti‐VEGF treatment alone. This work provides an alternative and effective method for noninvasive treatment for diabetic retinopathy. [Image: see text] |
| format | Online Article Text |
| id | pubmed-9875679 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-98756792023-01-25 Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) Li, Ya‐Nan Liang, Hong‐Wen Zhang, Chun‐Lin Qiu, Yan‐Mei Wang, David Wang, Hai‐Ling Chen, An‐Qi Hong, Can‐Dong Wang, Lei Wang, Hao Hu, Bo Adv Sci (Weinh) Inside Front Cover Smart Supramolecular Peptides In article number 2203351, Lei Wang, Hao Wang, Bo Hu, and co‐workers report the formulation of a smart supramolecular peptide (SSP) eye drop for diabetic retinopathy treatment that is effective via specifically identifying and capturing Semaphorin4D (Sema 4D), a strongly pro‐angiogenesis and exudates factor. The combination of SSP eye drop and anti‐vascular endothelial growth factor (VEGF) injection showed approximately two times better therapeutic effect over anti‐VEGF treatment alone. This work provides an alternative and effective method for noninvasive treatment for diabetic retinopathy. [Image: see text] John Wiley and Sons Inc. 2023-01-25 /pmc/articles/PMC9875679/ http://dx.doi.org/10.1002/advs.202370012 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Inside Front Cover Li, Ya‐Nan Liang, Hong‐Wen Zhang, Chun‐Lin Qiu, Yan‐Mei Wang, David Wang, Hai‐Ling Chen, An‐Qi Hong, Can‐Dong Wang, Lei Wang, Hao Hu, Bo Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) |
| title | Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) |
| title_full | Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) |
| title_fullStr | Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) |
| title_full_unstemmed | Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) |
| title_short | Ophthalmic Solution of Smart Supramolecular Peptides to Capture Semaphorin 4D against Diabetic Retinopathy (Adv. Sci. 3/2023) |
| title_sort | ophthalmic solution of smart supramolecular peptides to capture semaphorin 4d against diabetic retinopathy (adv. sci. 3/2023) |
| topic | Inside Front Cover |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875679/ http://dx.doi.org/10.1002/advs.202370012 |
| work_keys_str_mv | AT liyanan ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT lianghongwen ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT zhangchunlin ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT qiuyanmei ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT wangdavid ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT wanghailing ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT chenanqi ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT hongcandong ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT wanglei ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT wanghao ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 AT hubo ophthalmicsolutionofsmartsupramolecularpeptidestocapturesemaphorin4dagainstdiabeticretinopathyadvsci32023 |