CRISPR-based assays for low-resource settings

CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays and offer insights into how to surmount them.

Detalles Bibliográficos
Autores principales: Huang, Zhen, Lyon, Christopher J., Hu, Tony Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875755/
https://www.ncbi.nlm.nih.gov/pubmed/37064656
http://dx.doi.org/10.1038/s44222-023-00026-8
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author Huang, Zhen
Lyon, Christopher J.
Hu, Tony Y.
author_facet Huang, Zhen
Lyon, Christopher J.
Hu, Tony Y.
author_sort Huang, Zhen
collection PubMed
description CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays and offer insights into how to surmount them.
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spelling pubmed-98757552023-01-25 CRISPR-based assays for low-resource settings Huang, Zhen Lyon, Christopher J. Hu, Tony Y. Nat Rev Bioeng Comment CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays and offer insights into how to surmount them. Nature Publishing Group UK 2023-01-25 2023 /pmc/articles/PMC9875755/ /pubmed/37064656 http://dx.doi.org/10.1038/s44222-023-00026-8 Text en © Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Huang, Zhen
Lyon, Christopher J.
Hu, Tony Y.
CRISPR-based assays for low-resource settings
title CRISPR-based assays for low-resource settings
title_full CRISPR-based assays for low-resource settings
title_fullStr CRISPR-based assays for low-resource settings
title_full_unstemmed CRISPR-based assays for low-resource settings
title_short CRISPR-based assays for low-resource settings
title_sort crispr-based assays for low-resource settings
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875755/
https://www.ncbi.nlm.nih.gov/pubmed/37064656
http://dx.doi.org/10.1038/s44222-023-00026-8
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AT lyonchristopherj crisprbasedassaysforlowresourcesettings
AT hutonyy crisprbasedassaysforlowresourcesettings

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