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Nephron deficit and low podocyte density increase risk of albuminuria and glomerulosclerosis in a model of diabetes

Podocytes are terminally differentiated epithelial cells in glomeruli. Podocyte injury and loss are features of many diseases leading to chronic kidney disease (CKD). The developmental origins of health and disease hypothesis propose an adverse intrauterine environment can lead to CKD later in life,...

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Detalles Bibliográficos
Autores principales: Gazzard, Sarah E., van der Wolde, James, Haruhara, Kotaro, Bertram, John F., Cullen‐McEwen, Luise A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875819/
https://www.ncbi.nlm.nih.gov/pubmed/36695822
http://dx.doi.org/10.14814/phy2.15579