Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding

Undifferentiated osteoclast-like giant cell carcinomas (UOLGCCs) of the digestive tract are very rare, with only a few cases reported in the literature. An 82-year-old man was referred to the emergency department for melena. Endoscopic examination revealed a hemicircumferential ulcerovegetative lesi...

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Autores principales: Ventura, Sofia, Rodrigues, Pedro, Cancela, Eugénia, Carvalho, Ana Catarina, Rodrigues, Cláudio, Domingues, Ângela, Pinho, Juliana, Martins, Diana, Silva, Américo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875979/
https://www.ncbi.nlm.nih.gov/pubmed/36713281
http://dx.doi.org/10.14309/crj.0000000000000975
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author Ventura, Sofia
Rodrigues, Pedro
Cancela, Eugénia
Carvalho, Ana Catarina
Rodrigues, Cláudio
Domingues, Ângela
Pinho, Juliana
Martins, Diana
Silva, Américo
author_facet Ventura, Sofia
Rodrigues, Pedro
Cancela, Eugénia
Carvalho, Ana Catarina
Rodrigues, Cláudio
Domingues, Ângela
Pinho, Juliana
Martins, Diana
Silva, Américo
author_sort Ventura, Sofia
collection PubMed
description Undifferentiated osteoclast-like giant cell carcinomas (UOLGCCs) of the digestive tract are very rare, with only a few cases reported in the literature. An 82-year-old man was referred to the emergency department for melena. Endoscopic examination revealed a hemicircumferential ulcerovegetative lesion, involving the bulbar apex and extending to the second portion of the duodenum; biopsies revealed an UOLGCC. The patient underwent transfusion support therapy, and he was proposed for best supportive care. Duodenal UOLGCC is an extremely rare cause of upper gastrointestinal bleeding. Clinical findings and therapeutic approach represent a challenge in this pathology.
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spelling pubmed-98759792023-01-26 Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding Ventura, Sofia Rodrigues, Pedro Cancela, Eugénia Carvalho, Ana Catarina Rodrigues, Cláudio Domingues, Ângela Pinho, Juliana Martins, Diana Silva, Américo ACG Case Rep J Case Report Undifferentiated osteoclast-like giant cell carcinomas (UOLGCCs) of the digestive tract are very rare, with only a few cases reported in the literature. An 82-year-old man was referred to the emergency department for melena. Endoscopic examination revealed a hemicircumferential ulcerovegetative lesion, involving the bulbar apex and extending to the second portion of the duodenum; biopsies revealed an UOLGCC. The patient underwent transfusion support therapy, and he was proposed for best supportive care. Duodenal UOLGCC is an extremely rare cause of upper gastrointestinal bleeding. Clinical findings and therapeutic approach represent a challenge in this pathology. Wolters Kluwer 2023-01-25 /pmc/articles/PMC9875979/ /pubmed/36713281 http://dx.doi.org/10.14309/crj.0000000000000975 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Ventura, Sofia
Rodrigues, Pedro
Cancela, Eugénia
Carvalho, Ana Catarina
Rodrigues, Cláudio
Domingues, Ângela
Pinho, Juliana
Martins, Diana
Silva, Américo
Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding
title Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding
title_full Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding
title_fullStr Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding
title_full_unstemmed Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding
title_short Undifferentiated Carcinoma With Osteoclast-Like Giant Cells: A Rare Cause of Upper Gastrointestinal Bleeding
title_sort undifferentiated carcinoma with osteoclast-like giant cells: a rare cause of upper gastrointestinal bleeding
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875979/
https://www.ncbi.nlm.nih.gov/pubmed/36713281
http://dx.doi.org/10.14309/crj.0000000000000975
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