Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient

Many chemotherapeutic agents have been associated with drug-induced colitis (DIC). With newer agents' expansion of approval as first-line therapy for common cancers, it is important to be cognizant of their association with DIC. We present a case of brentuximab-associated DIC in an elderly woma...

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Autores principales: Ali, Sareena, AbdulMujeeb, Sufyan, Khattab, Ahmed, Asado, Nahren, Fine, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876007/
https://www.ncbi.nlm.nih.gov/pubmed/36713279
http://dx.doi.org/10.14309/crj.0000000000000974
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author Ali, Sareena
AbdulMujeeb, Sufyan
Khattab, Ahmed
Asado, Nahren
Fine, Marc
author_facet Ali, Sareena
AbdulMujeeb, Sufyan
Khattab, Ahmed
Asado, Nahren
Fine, Marc
author_sort Ali, Sareena
collection PubMed
description Many chemotherapeutic agents have been associated with drug-induced colitis (DIC). With newer agents' expansion of approval as first-line therapy for common cancers, it is important to be cognizant of their association with DIC. We present a case of brentuximab-associated DIC in an elderly woman with CD30+ Hodgkin lymphoma. Brentuximab's association with DIC was suspected by others in the literature, but a history of stem-cell transplant in them would blur the association with graft-vs-host disease. Lack of stem-cell transplant in our patient makes the link between brentuximab and DIC unambiguous.
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spelling pubmed-98760072023-01-26 Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient Ali, Sareena AbdulMujeeb, Sufyan Khattab, Ahmed Asado, Nahren Fine, Marc ACG Case Rep J Case Report Many chemotherapeutic agents have been associated with drug-induced colitis (DIC). With newer agents' expansion of approval as first-line therapy for common cancers, it is important to be cognizant of their association with DIC. We present a case of brentuximab-associated DIC in an elderly woman with CD30+ Hodgkin lymphoma. Brentuximab's association with DIC was suspected by others in the literature, but a history of stem-cell transplant in them would blur the association with graft-vs-host disease. Lack of stem-cell transplant in our patient makes the link between brentuximab and DIC unambiguous. Wolters Kluwer 2023-01-25 /pmc/articles/PMC9876007/ /pubmed/36713279 http://dx.doi.org/10.14309/crj.0000000000000974 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Ali, Sareena
AbdulMujeeb, Sufyan
Khattab, Ahmed
Asado, Nahren
Fine, Marc
Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient
title Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient
title_full Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient
title_fullStr Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient
title_full_unstemmed Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient
title_short Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient
title_sort brentuximab-induced colitis in a non-stem-cell transplant patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876007/
https://www.ncbi.nlm.nih.gov/pubmed/36713279
http://dx.doi.org/10.14309/crj.0000000000000974
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AT asadonahren brentuximabinducedcolitisinanonstemcelltransplantpatient
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