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Impact of valproic acid on busulfan pharmacokinetics: In vitro assessment of potential drug-drug interaction
Busulfan (Bu) is an alkylating agent commonly used at high doses in the preparative regimens of hematopoietic stem cell transplantation (HSCT). It has been shown that such high doses of Bu are associated with generalized seizures which are usually managed by prophylactic antiepileptic drugs (AEDs) s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876357/ https://www.ncbi.nlm.nih.gov/pubmed/36696427 http://dx.doi.org/10.1371/journal.pone.0280574 |