Cargando…

Cortical-blood vessel assembloids exhibit Alzheimer’s disease phenotypes by activating glia after SARS-CoV-2 infection

A correlation between COVID-19 and Alzheimer’s disease (AD) has been proposed recently. Although the number of case reports on neuroinflammation in COVID-19 patients has increased, studies of SARS-CoV-2 neurotrophic pathology using brain organoids have restricted recapitulation of those phenotypes d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Dasom, Park, Ki Hoon, Kim, Da-Hyun, Kim, Nam Gyo, Lee, Seung-Eun, Shin, Nari, Kook, Myung Geun, Kim, Young Bong, Kang, Kyung-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876421/ https://www.ncbi.nlm.nih.gov/pubmed/36697403 http://dx.doi.org/10.1038/s41420-022-01288-8

Ejemplares similares

CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
por: Li, Emmy, et al.
Publicado: (2023)

Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C
por: Lee, Seung-Eun, et al.
Publicado: (2020)

Generation of Cortical Brain Organoid with Vascularization by Assembling with Vascular Spheroid
por: Kook, Myung Geun, et al.
Publicado: (2022)

Zika virus infection accelerates Alzheimer’s disease phenotypes in brain organoids
por: Lee, Seung-Eun, et al.
Publicado: (2022)

Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids
por: Park, Yoonseok, et al.
Publicado: (2021)

Pimecrolimus interferes the therapeutic efficacy of human mesenchymal stem cells in atopic dermatitis by regulating NFAT-COX2 signaling
por: Shin, Nari, et al.
Publicado: (2021)

Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer’s disease
por: Lee, Seung-Eun, et al.
Publicado: (2022)

Spatially controlled construction of assembloids using bioprinting
por: Roth, Julien G., et al.
Publicado: (2023)

Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis
por: Nam, Donggyu, et al.
Publicado: (2022)

Repeated intramuscular transplantations of hUCB-MSCs improves motor function and survival in the SOD1 G(93)A mice through activation of AMPK
por: Kook, Myung Geun, et al.
Publicado: (2020)

Imaging neuronal migration and network activity in human forebrain assembloids
por: Birey, Fikri, et al.
Publicado: (2022)

Generation of human gastric assembloids from primary fetal organoids
por: Benedetti, Giada, et al.
Publicado: (2023)

Astrocytic scar restricting glioblastoma via glutamate–MAO-B activity in glioblastoma-microglia assembloid
por: Diep, Yen N., et al.
Publicado: (2023)

The role of Jagged1 as a dynamic switch of cancer cell plasticity in PDAC assembloids
por: Choi, Jae-Il, et al.
Publicado: (2022)

Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids
por: Rawlings, Thomas M, et al.
Publicado: (2021)

From Brain Organoids to Networking Assembloids: Implications for Neuroendocrinology and Stress Medicine
por: Makrygianni, Evanthia A., et al.
Publicado: (2021)

Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment
por: Meng, Xiangling, et al.
Publicado: (2023)

Deleterious Alteration of Glia in the Brain of Alzheimer’s Disease
por: Kim, Eunyoung, et al.
Publicado: (2020)

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids
por: Ai, Zongyong, et al.
Publicado: (2023)

Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model
por: Rickner, Hannah Drew, et al.
Publicado: (2022)

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche
por: Lin, Manqiang, et al.
Publicado: (2023)

Neuro-mesodermal assembloids recapitulate aspects of peripheral nervous system development in vitro
por: Rockel, Anna F., et al.
Publicado: (2023)

Exploring glia to better understand Alzheimer’s disease
por: Kim, Yoo Sung, et al.
Publicado: (2018)

Electrophysiological Activity of Primary Cortical Neuron-Glia Mixed Cultures
por: Goshi, Noah, et al.
Publicado: (2023)

Activity in a Premotor Cortical Nucleus of Zebra Finches Is Locally Organized and Exhibits Auditory Selectivity in Neurons but Not in Glia
por: Graber, Michael H., et al.
Publicado: (2013)

Superficial capillary plexus vessel density/deep capillary plexus vessel density ratio in healthy eyes
por: Nam, Ki-Yup, et al.
Publicado: (2022)

A Human 3D neural assembloid model for SARS-CoV-2 infection
por: Wang, Lu, et al.
Publicado: (2021)

Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells
por: Miura, Yuki, et al.
Publicado: (2020)

The Effect of a Novel Mica Nanoparticle, STB-MP, on an Alzheimer’s Disease Patient-Induced PSC-Derived Cortical Brain Organoid Model
por: Kim, Nam Gyo, et al.
Publicado: (2023)

Generation of Human Endometrial Assembloids with a Luminal Epithelium using Air–Liquid Interface Culture Methods
por: Tian, Jiwen, et al.
Publicado: (2023)

Editorial: The Role of Glia in Alzheimer's Disease
por: Pérez-Nievas, Beatriz G., et al.
Publicado: (2019)

Deciphering Neuron-Glia Compartmentalization in Cortical Energy Metabolism
por: Jolivet, Renaud, et al.
Publicado: (2009)

The colocatome as a spatial -omic reveals shared microenvironment features between tumour–stroma assembloids and human lung cancer
por: Bouchard, Gina, et al.
Publicado: (2023)

COVID-19 vaccination-related small vessel vasculitis with multiorgan involvement
por: Kim, Yunkyung, et al.
Publicado: (2022)

NG2 glia are required for vessel network formation during embryonic development
por: Minocha, Shilpi, et al.
Publicado: (2015)

Crosstalk between Blood Vessels and Glia during the Central Nervous System Development
por: Tabata, Hidenori
Publicado: (2022)

Glia-Driven Neuroinflammation and Systemic Inflammation in Alzheimer’s Disease
por: Hashioka, Sadayuki, et al.
Publicado: (2021)

New Method for Simultaneous Quantification of 12 Ginsenosides in Red Ginseng Powder and Extract: In-house Method Validation
por: In, Gyo, et al.
Publicado: (2012)

CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes
por: Kim, Jihwa, et al.
Publicado: (2018)

Seizure-Related Cortical Volume Alterations in Alzheimer’s Disease: A Preliminary Study
por: Hahm, Jarang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2h2563ciqjm9lpb9ma6grdnkrm