Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases

Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. When bone homeostasis is broken, it can manifest as osteoarthritis (OA), rheumatoid arthritis (RA), osteosarcoma (OS), etc. MiR-671, an important class of non-coding nucleotide sequences in vivo, is re...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shaotai, Hu, Min, Song, Dongsheng, Tang, Linjun, Jiang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876598/
https://www.ncbi.nlm.nih.gov/pubmed/36713572
http://dx.doi.org/10.3389/fonc.2022.1018308
_version_ 1784878198288285696
author Wang, Shaotai
Hu, Min
Song, Dongsheng
Tang, Linjun
Jiang, Huan
author_facet Wang, Shaotai
Hu, Min
Song, Dongsheng
Tang, Linjun
Jiang, Huan
author_sort Wang, Shaotai
collection PubMed
description Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. When bone homeostasis is broken, it can manifest as osteoarthritis (OA), rheumatoid arthritis (RA), osteosarcoma (OS), etc. MiR-671, an important class of non-coding nucleotide sequences in vivo, is regulated by lncRNA and regulates bone metabolism balance by regulating downstream target proteins and activating various signaling pathways. Based on the structure and primary function of miR-671, this paper summarizes the effect and mechanism of miR-671 in bone-related inflammation and cancer diseases, and prospects the application possibility of miR-671, providing reference information for targeted therapy of bone-related disorders.
format Online
Article
Text
id pubmed-9876598
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-98765982023-01-26 Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases Wang, Shaotai Hu, Min Song, Dongsheng Tang, Linjun Jiang, Huan Front Oncol Oncology Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. When bone homeostasis is broken, it can manifest as osteoarthritis (OA), rheumatoid arthritis (RA), osteosarcoma (OS), etc. MiR-671, an important class of non-coding nucleotide sequences in vivo, is regulated by lncRNA and regulates bone metabolism balance by regulating downstream target proteins and activating various signaling pathways. Based on the structure and primary function of miR-671, this paper summarizes the effect and mechanism of miR-671 in bone-related inflammation and cancer diseases, and prospects the application possibility of miR-671, providing reference information for targeted therapy of bone-related disorders. Frontiers Media S.A. 2023-01-11 /pmc/articles/PMC9876598/ /pubmed/36713572 http://dx.doi.org/10.3389/fonc.2022.1018308 Text en Copyright © 2023 Wang, Hu, Song, Tang and Jiang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Wang, Shaotai
Hu, Min
Song, Dongsheng
Tang, Linjun
Jiang, Huan
Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
title Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
title_full Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
title_fullStr Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
title_full_unstemmed Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
title_short Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
title_sort research progress on the role and mechanism of mir-671 in bone metabolism and bone-related diseases
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876598/
https://www.ncbi.nlm.nih.gov/pubmed/36713572
http://dx.doi.org/10.3389/fonc.2022.1018308
work_keys_str_mv AT wangshaotai researchprogressontheroleandmechanismofmir671inbonemetabolismandbonerelateddiseases
AT humin researchprogressontheroleandmechanismofmir671inbonemetabolismandbonerelateddiseases
AT songdongsheng researchprogressontheroleandmechanismofmir671inbonemetabolismandbonerelateddiseases
AT tanglinjun researchprogressontheroleandmechanismofmir671inbonemetabolismandbonerelateddiseases
AT jianghuan researchprogressontheroleandmechanismofmir671inbonemetabolismandbonerelateddiseases

Ejemplares similares