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Inhibition of Mast Cell Degranulation in Atopic Dermatitis by Celastrol through Suppressing MRGPRX2
BACKGROUND: Atopic dermatitis is a common dermatological disease, and mast cell degranulation is believed to be related with the progression of atopic dermatitis. Mas-related G protein-coupled receptor-X2 (MRGPRX2), and calcium release-activated calcium channel protein 1-2 (ORAI-1, ORAI-2) are invol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876689/ https://www.ncbi.nlm.nih.gov/pubmed/36712922 http://dx.doi.org/10.1155/2023/9049256 |