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Inhibition of Mast Cell Degranulation in Atopic Dermatitis by Celastrol through Suppressing MRGPRX2

BACKGROUND: Atopic dermatitis is a common dermatological disease, and mast cell degranulation is believed to be related with the progression of atopic dermatitis. Mas-related G protein-coupled receptor-X2 (MRGPRX2), and calcium release-activated calcium channel protein 1-2 (ORAI-1, ORAI-2) are invol...

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Detalles Bibliográficos
Autores principales:	Yao, Ciyu, Ye, Wenzhen, Chen, Mengxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876689/ https://www.ncbi.nlm.nih.gov/pubmed/36712922 http://dx.doi.org/10.1155/2023/9049256

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